LEC Biopsy Tool Group Members: Hiroki Meguro Amine Hallab Kevin Mihelc Jen Bacior Advisors: Kelly Dympna, MD John Patzer, PhD 22 March 2005

1
LEC Biopsy ToolGroup MembersHiroki
MeguroAmine HallabKevin MihelcJen
BaciorAdvisorsKelly Dympna, MDJohn Patzer,
PhD22 March 2005
2
Project Overview

• Intended Use Open Liver Biopsy
• Basic Functions
• 1). Tissue excision
• 2). Cauterization
• 3). Biopsy Tissue Protection

3
Personal Responsibilities

• Market Research
• Initial LEC Design
• Assist in Testing
• Overall Design History File Update

4
Personal Milestones

• Market Research Done
• Initial LEC Blade Design Done
• Assist in Prototype Testing March 28th April
  11th
• Revise DHF Week of April 4th

5
Market Research

• 25 million people in America are affected by
  acute and chronic liver disease
• Liver biopsy is an essential tool in studying,
  categorizing and eventually curing liver disease
• There is an emerging need for a tool that will be
  useful when spot-probe freezing has been used
  prior to biopsy
• In 2001, alone, 262 million was spent on liver
  research

6
Initial LEC Blade Design

• Geometric approach
• 1. Triangle shape in order to excise the
• tissue as a wedge
• 2. Allows for a very sharp edge to prevent
• tissue damage

7
Initial LEC Design
Blades
8
LEC Design Transition
9
Prototype Testing

• Determine criteria to adjudicate success of
  prototype
• Accuracy of cut
• Speed of cauterization
• Final temperature of biopsy tissue
• Ease of use

10
Overall Design History File Update

• Revise and Update file to confirm proper
  development of the LEC Biopsy Tool

11
Acknowledgements

• Professor Mark Gartner
• Kelly Dympna, MD
• John Patzer, PhD
• LEC Group Menbers
• Department of Bioengineering

12
Questions ??