Computer Graphics and Applications

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Computer Graphics and Applications

• Tao Ju, Cindy Grimm
• Dept. of Computer Science and Engineering
• Washington University in St. Louis

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What is CG?
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Our Areas

• Modeling (Cindy, Tao)
• Shape understanding (Tao)
• Animation (Tao)
• Art-based rendering (Cindy)
• Bio-medical applications (Cindy, Tao)
• Collaborators

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Polygonal Models

• Digital representation of surfaces using polygons
• Triangles, quads, etc.
• Applications
• Movies, games
• Visualization
• Simulation

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Building Models
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Building Models

• In Action!
• Real-time model construction in games

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Repairing Models
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Shape Understanding

• Using skeletons to identify shape components
• Highlights tubular and plate-like parts Ju et
  al. 07,08,09

Surface
Plate-like
Curve
Tubular
3D Object
Skeleton
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Animation
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Animation

• Cage-based character control

Siggraph 05
Deforming the cage
Model cage
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Animation

• Cage-based character control

Siggraph 05
Deforming the cage
Model cage
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Animation

• In Action!

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Animation

• Designing interesting skin behaviors with cages
• And use it on different models

Siggraph Asia 08
A muscle bulging
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Art-based rendering(Cindy)

• Motivation Artists study how to convey
  information in non-verbal ways
• E.g. Caricatures.
• Easily recognizable faces (faster recognition
  than a photograph)

John S. Pritchett, artist
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Art-based rendering(Cindy)

• Replicate existing media
• Paint, line drawings, mazes
• Automatic or manual
• Rendering styles for visual clarity
• Silhouettes, stipples, warm-cool lighting

Barb Meier, Painterly Rendering, Siggraph 1996
Craig Kaplan, Maze Design, Siggraph 2007
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Art-based rendering(Cindy)

• Abstraction

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Art-based rendering(Cindy)

• Using texture and shading

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Art-based rendering(Cindy)

• Non-linear cameras

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Bio-Med 1 Protein Modeling

• Protein a sequence of amino acids
• Folds into a 3D structure in order to interact
  with other molecules
• Protein function derived from its 3D structure
• Why do we care?
• E.g., understanding and inhibiting virus

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Bio-Med 1 Protein Modeling

• Imaging Computing

Electron Cryo-Microscopy
3D image of a virus
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Bio-Med 1 Protein Modeling

• Skeleton-based approach

CAD 07, Structure 07, CAD 08, SMI 08
Plate
Surface
ß-sheet
Tube
Curve
a-helix
Cryo-EM Volume
Skeleton
Protein Structure
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Bio-Med 1 Protein Modeling

• Recent progress

Backbone structure of the infectious e15 virus
capsid Jiang et. al., Nature 2008
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Bio-Med 2 Gene Mapping

• Gene
• Blueprints for creating proteins
• 20,000 in human as well as in mouse
• Gene expression
• Where a particular gene is active
• A key to understand what a gene does and how it
  relates to other genes
• The foundation of developing cures for genetic
  disorders

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Bio-Med 2 Gene Mapping

• Imaging Computing

Gene Hnt
In-situ hybridization
Gene Calb
Gene Sst
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Bio-Med 2 Gene Mapping

• Imaging Computing
• Atlas-based image comparison

SGP 03, PLoS 06, IEEE TMI 07
Graphical search interface
Query results
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Bio-Med 2 Gene Mapping

• Mapping 3D gene expression patterns
• Building 3D anatomical atlas
• Performing 3D spatial queries

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Summary

• Computer graphics
• Modeling, animation, rendering
• Computational bio-medicine