Title: Gene regulation in prokaryotes
1Gene regulation in prokaryotes
2Inducible transcription lac operon
3Inducible transcription lac operon
4Transcription termination by attenuation trp
operon
5Transcription termination by attenuation
Two possible base-pairing schemes within the mRNA
at the beginning of the trp operon
6Transcription termination by attenuation
Not enough tryptophan amino acids causes ribosome
to stall on the mRNA ? allows pre-emptor stemloop
to form ? termination does not occur
Moving ribosome ? pre-emptor structure does not
form terminator stemloop forms terminates
transcription of the rest of the mRNA
7Regulation in phage lambda(?)
8Regulation in phage lambda(?)