Helen Wills

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TOP-DOWN PREFRONTAL CONTROL of SENSORY
PROCESSING Bob Knight Department of
Psychology Helen Wills Neuroscience
Institute UC Berkeley
Helen Wills 8-time Wimbledon champion
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FRONTAL SUBDIVISIONS
Ventromedial BA 10, 32, 33,
Orbitofrontal BA 11, 12, 13, 47
Dorsolateral BA 46, 9, 10
Orbitofrontal Cortex BA 11, 12, 13, 47
Ventrolateral BA 44, 45, 47
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LATERAL LESIONS
FRONTAL STROKE
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FULL FIELD ATTENTION
Target
Standard
Novel
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STANDARDS
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EARLY TOP DOWN MODULATION
?
? Tonic or Attention Dependent Input 100msec
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Target
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TARGETS
N2

N1

-
m
2

V


P3b
0
800
400
ms
m
3

V
FRONTALS
CONTROLS
m
- 3
V
CONTROLS
FRONTALS
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(No Transcript)
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LATE TOP DOWN MODULATION
? Tonic or Attention Dependent Input 100msec
Target Detection 200-800 msec
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HEMIFIELD ATTENTION
Yago et al, in press
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PURE ATTENTION ACTIVITY (Attend-Ignore)
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TOP DOWN MODULATION
? Tonic or Attention Dependent Input 100msec
Tonic Excitatory Input Onset 100msec
Target Detection 200-800 msec
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FRONTAL DEPENDENT LATE ATTENTION
N1
N2
P1
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THREE TOP DOWN MECHANISMS
Tonic Excitatory Input Onset 100 msec
Selective Attention 150- 350 msec
Template Match 200-800 msec
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INFERIOR PARIETAL EARLY ATTENTION
N1
N2
P1