Suppl Fig.1

1
A
GFX
PMA
C
PMA
B
GFX
2 pA
C
1 s
Supplementary Fig. 1 Facilitation of NSCMS
activity by phorbol 12-myristate 13-acetate (PMA)
and its inhibition by GF109203X (GFX) A, B.
Representative current traces recorded in a
cell-attached patch under continuous negative
pressure (-15 mmHg) at 50 mV. Times of PMA (100
nM) and GFX (10 mM) treatment are indicated by
bars above the typical current traces.
Suppl Fig.1
2
Slow increase of changes of outer diameter in
response to increases in intravascular pressure
from 5 to 10, 15 and 20 mmHg in control (1.8 mM
Ca2, left panel) and Ca2 free bath solution
(right panel).
Suppl Fig.2