PPARa activators lower small dense LDL

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PPARa activators lower small dense LDL
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Plasma triglyceride and cholesterol levelsfor
human apo A-V transgenic mice
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Plasma triglyceride and cholesterol levelsfor
apo A-V knockout mice
4
Allele frequencies for SNP 3 accordingto plasma
triglyceride levels
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PPARa activators induce apo A-V gene expression
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PPARa activates human apo A-Vtranscription
through two PPREs
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PPARa apo A-l, apo A-ll, LPL,ABCA-1 and SR-BI
expression
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PPARa activators induce ABCA-1 gene expressionin
human macrophages
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PPARa activators induce cholesterol effluxfrom
human macrophages