Improving Cancer Outcomes for AfricanAmericans

1
Improving Cancer Outcomes for African-Americans

• New Hanover Regional Medical Center
• Coastal Area Health Education Center
• University of North Carolina at Chapel Hill
• University of North Carolina at Wilmington
• Report given at the Program Steering Committee
  Meeting
• 22 June 2006, Toronto

2
Yearly Patient Accruals and Total Enrollment

• Clinical Trials (through Apr 2006)

3
Yearly Patient Accruals and Total Enrollment

• Navigated Patients (through Apr 2006)

4
Yearly Patient Accruals and Total Enrollment

• Psychological Study (closed 2005)

5
Status of Clinical Trials

• Head Neck trial
• Hyperfractionated IMR with weekly concurrent
  Cisplatin
• First investigator-initiated clinical trial at
  NHRMC
• 17 patients enrolled (3 black)
• Good early outcomes
• Treatment efficacy
• Potentially less toxicity

6
Additional Clinical Trials

• Small cell lung ca Chemo plus chest
  radiotherapy
• Ca of anal canal Chemo radiotherapy
• Prostate Ca (RTOG 0232) External beam plus
  brachytherapy versus brachytherapy alone
  (enrolled one black male in June)

7
Additional Clinical Trials

• Non-small cell lung ca Cranial irradiation vs
  observation
• Non-small cell lung ca Selenium supplementation
• Pancreatic ca (NSABP) Chemo radiotherapy vs
  chemo
• DCIS (NSABP) Anastrozole vs Tamoxifen

8
Peer-reviewed Publications

• Manuscripts in preparation
• Maguire, Hamann, Menon
• Prostate cancer risk groups and treatment choices
  (ASTRO poster)
• Maguire
• Treatment planning using TELESYNERGY (ATA
  presentation)
• Hamann, Mathews, Johnson
• Effects of cancer on cultural and social beliefs
  and attitudes (ASTRO poster)

9
Peer-reviewed Publications

• Manuscripts in preparation, contd
• Kotwall, Maguire, Dobson, Hamann
• Racial differences in rectal cancer outcomes
• Kotwall, Cyr
• Racial differences in frequency of breast
  conservation surgery and breast reconstruction in
  women with Stages 0,1, 2 breast cancer

10
Partnership Relations

• UNC-Chapel Hill
• visits to Chapel Hill by PI
• educational conferences
• patient consultations
• Second site for Head Neck trial

11
TELESYNERGY Use

• Educational conferences
• Treatment planning
• Meetings
• Two papers at ATA, May 2006
• Honaker, Maguire, Rosenman
• A Year a half of TELESYNERGY in southeastern
  NC
• Maguire
• TELESYNERGY Bridging academic and community
  radiology oncology treatment planning

12
Patient Navigator Program

• Active recruitment of patients
• Heavy schedule of outreach events
• Partnered with Prostate Cancer Screening project
• Staffing
• 2 ftes
• 2 volunteers
• Products
• Video
• brochure

13
Status of Psychological Research

• Conducted 260 interviews
• Analyzed 228 interviews
• Interventions based on results
• Web-based curriculum modules for MDs
• Clergy Day on Cancer
• Pending proposal
• Increasing the Utilization and Impact of the
  NCIs Cancer Information Service