Atherosclerosis

1
???? ??????Atherosclerosis
?????? ?????? ????? ?????? ???? ???
ARTERIOSCLEROSIS (???????? ??????)  ????? ?????
????? ATHEROSCLEROSIS ??????  ATHEROMA -
????. ?? ????? ??? ???? ??? ???? ????? ?????,
?????? ???????? ??? (???????) ?????? ???? ?????
????? ?????? ??????? ????? ??????? ?? ???????
??????? ?????? ??? ????? "???? ??????".  

This is a normal coronary artery with no
atherosclerosis and a widely patent lumen that
can carry as much blood as the myocardium
requires.
2
This is mild coronary atherosclerosis. A few
scattered yellow lipid plaques are seen on the
intimal surface of the opened coronary artery
traversing the epicardial surface of a heart. The
degree of atherosclerosis here is not significant
enough to cause disease, but could be the
harbinger of worse atherosclerosis to come.
3
The degree of atherosclerosis is much greater in
this coronary artery, and the lumen is narrowed
by half. A small area of calcification is seen in
the plaque at the right.
4
These cross sections of the left anterior
descending coronary artery demonstrate more
pronounced atherosclerosis with narrowing at the
left, which is the proximal portion of this
artery. Atherosclerosis is generally worse at the
beginning of an artery where turbulence is
greater.
5
Here is occlusive coronary atherosclerosis. The
coronary at the left is narrowed by 60 to 70.
The coronary at the right is even worse with
evidence for previous thrombosis with
organization of the thrombus and recanalization
such that there are three small lumens remaining.
6
Here is a coronary artery with atherosclerotic
plaques. There is hemorrhage into the plaque in
the middle of this photograph. This is one of the
complications of atherosclerosis. Such hemorrhage
could acutely narrow the lumen.
7
This is the gross appearance of severe coronary
atherosclerosis, which involves virtually 100 of
the surface of the coronary. There is extensive
calcification, especially at the right where the
lumen is narrowed.
8
This is coronary thrombosis, one of the
complications of atherosclerosis. The dark red
thrombus is seen in the anterior descending
coronary artery
9
Here is the coronary thrombosis at higher
magnification. The thrombus occludes the lumen
and produces ischemia and/or infarction of the
myocardium.
10
Look carefully at this aorta. The white arrow
denotes the most prominent fatty streak in the
photo, but there are other fatty streaks
scattered over the aortic surface. Fatty streaks
are the earliest lesions seen with
atherosclerosis in arteries. Increased total
cholesterol and decreased HDL cholesterol
contribute to this process.
11
A coronary thrombosis is seen microscopically
occluding the remaining small lumen of this
coronary artery. ???? Golden Hour - Medical
Information center