Perspectives on the CTSA Program: Views from NIH

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National Center forResearch Resources
A c c e l e r a t i n g a n d e n h a n c i
n g r e s e a r c h f r o m b a s i c d i
s c o v e r y t o i m p r o v e d p a t I e
n t c a r e
NATIONAL INSTITUTES OF HEALTH
Perspectives on the CTSA Program Views from
NIH April 11, 2008
Barbara Alving, M.D., M.A.C.P. Director National
Center for Research Resources
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National Center for Research Resources
Biomedical Technology
Comparative Medicine
Clinical Research
Research Infrastructure
www.ncrr.nih.gov
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CTSAs Building a National Consortium
Case Western Reserve University
University ofPittsburgh
University of Michigan
University of Washington
University of Rochester
Oregon Health Science University
Mayo ClinicCollege ofMedicine
Yale University
Weill Cornell Medical College
Columbia University
University of Wisconsin
University of Iowa
Rockefeller University
University of California, Davis
University ofChicago
University of Pennsylvania
University of California, San Francisco
Washington University,in St. Louis
Johns Hopkins University
Vanderbilt University
Duke University
Emory University
University of TexasSouthwestern Medical Center
University of Texas Health Science Center at
Houston
Participating Institutions
Since 2006
Since 2007
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Consortium Pilot ProjectsWest Coast Alliance
Meeting planned by Oregon Health and Science
University and University of California, Davis

• 56 representatives from all four west coast
  CTSA institutions

• Presentations from each CTSA site
• Opportunities to collaborate and share
  strengths
• Discussion of building investigator and
  scientific collaborationsopportunities across
  centers

• Program-focused breakout sessions

University of Washington Oregon Health and
Science University University of California,
Davis University of California, San Francisco
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Consortium Pilot ProjectsWest Coast Consortium
Results from break-out sessions

• Monthly discussions between Informatics groups at
  OHSU and UCD
• Collaborations on specific Informatics projects
  across the four centers
• Focus on development of core competencies in
  Research education reciprocal reviews of K12
  applications OHSU/UCD
• Community engagement planning of regional
  workshop
• Generally personal interaction and knowledge of
  center strengths and focus lowers barriers for
  interaction

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CTSA Governance
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Public-Private Partnerships - Mission

• Facilitate the implementation of partnerships
  with industry, other academia and patient
  advocacy groups, to support and conduct medical
  research, research training and the dissemination
  of information by

• Sharing best practices across the CTSA consortium
• Coordinating CTSA consortium-wide exchange of
  information
• Providing assistance with new or established
  partnerships to identify partners and partnership
  models

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Public-Private Partnerships (PPP) ExampleThe
West Coast Licensing Partnership

• Adds value by bundling related technologies over
  individual tools and technologies
• Strengthens inter-institutional relationships
  between member partners
• Increases global access to research tools by
  promotion of non-exclusive licensing
• Provides simple one-stop licensing of
  technologies from multiple institutions
• Saves time and money from negotiating multiple
  license agreements

• Oregon CTSA is part of a group of institutions
  willing to designate a subset of their
  technologies for marketing and licensing purposes

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CTSA Pilot Projects

• TRaining And Nurturing Scientists FOr
  
• Research that is Multidisciplinary
• (TRANSFORM) Program
• By bringing diverse scientists together at the
  beginning of their scientific career, we believe
  we can forge new collaborations and
  multidisciplinary teams to tackle the large,
  complex public health challenges we face.
• Karin Davidison, Ph.D.
• Co-Director, TRANSFORM

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Women in Biomedical Research Workforce
Loss (Need to Track Career Success of K12
Scholars by Gender)
90
- clinical
80
- basic science
70
60
38
27
15
8.5
36
29
18
21
13
50
49
43
50
40
30
20
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Resid
Assist Prof
Assoc Prof
Full Prof
Div Chief
Dept Chair
Med Sch Apps
Med Sch Grads
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NCRR Budget Comparisons
GCRC
CTSA
GCRC
NPRC
BTRR
IDeA
RCMI
GCRC
2005
Other
CTSA
2008
CTSA
While funding for clinical and translational
research is increasing, NCRR will maintain a
balanced research portfolio.
2012 (est.)
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Funding Comparison Centers vs. RPGs
N
H
L
B
I


N
C
R
R


F
Y

2
0
0
8

(
e
s
t
.
)
F
Y

2
0
0
8

(
e
s
t
.
)
92 of Funding
8 of Funding
7 of Funding
Center Grants 141M RPGs 2B
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Connecting Resources through the CTSA Consortium

• Opportunities to collaborate with
• Private and public organizations
• Research Centers in Minority
  Institutions
• Underserved populations through Institutional
  Development Award (IDeA) States
• National Primate Research Centers
• National Cancer Institute - Cancer Centers

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Institutional Development Award (IDeA)Increasing
research capacity in 23 underserved states and
Puerto Rico
Montana State University
Universityof Idaho
University of Wyoming
University of Nevada, Reno
Universityof Alaska
Universityof Hawaii
Lariat Project encircling institutions with
connectivity IDeA-eligible states
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Research Centers in Minority Institutions (RCMIs)
18 Centers in 10 states, the District of
Columbia, and Puerto Rico
City College CUNY
Hunter College CUNY
Morgan State University, MD
Howard University, DC
Meharry Medical College, TN
Charles R. Drew University, CA
Clark Atlanta University, GA
Morehouse School of Medicine, GA
University of Texasat El Paso
Florida AM University
Tuskegee University, AL
Jackson State University, MS
University of Hawaii at Manoa
University of Texas at San Antonio
University of Puerto Rico, Medical Sciences
Campus
Texas Southern University
Universidad Central del Caribe, PR
RCMIs
Ponce School of Medicine, PR
RCMI/RCMI Clinical Research Centers
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NIH Funded ProjectsUsing NCRR Resources
(CTSAs need to show value to the other ICs)
Data obtained from FY 2007 Annual Progress Reports
(millions)
Based on FY 2007 Appropriation
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National Institutes of HealthFY 2007 and FY 2008
Budget(dollars in thousands)
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National Center for Research Resources

• Accelerating and enhancing research from basic
  discovery to improved patient care