Mobile genetic elements and adaptive mutation

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Mobile genetic elements and adaptive mutation
Miki Lee / OEB 192 08.11.12
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IS family
http//www-is.biotoul.fr/
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Effects on bacterial evolution

• An important source of genetic variation
• Insertion
• Homologous recombination

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Effects on bacterial evolution
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M-evolved S-evolved MS-evolved
M/S-evolved
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Mutation
LuriaDelbrück experiment
CairnsFoster system
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Modified CairnsFoster system
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Kugelberg E. et.al. PNAS 200610317319-17324
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Monday (11/17) Physiological basis of fitness
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Upcoming talks Tuesday, 12/16 Rich
Lenski Michigan State University 1230 pm, 341
Warren Alpert (HMS)