Urinary system

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Stephen E. Fish, Ph.D. Mitchell L. Berk,
Ph.D. Marshall University J. C. E. School of
Medicine
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Note to instructors I use these PowerPoint
slides in histology lectures that I give to first
year medical students. Copy the slides, or just
the images into your own teaching media. We all
know that teaching science often requires
compromises and simplification for specific
student populations, or the requirements of a
specific course. Please feel free to offer
suggestions for improvements, corrections, or
additional illustrations. I would be pleased to
hear from anyone who finds my work useful, and am
always willing to make it better. Also, the
images have been compressed to screen resolution
to keep PowerPoint file size down, and I can
provide them at any resolution. Contact me about
the illustrations and Mitchell L. Berk about the
photomicrographs. Stephen E. Fish,
Ph.D. Fish_at_Marshall.edu Berk_at_Marshall.edu
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Urinary system
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Kidney overview
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Kidney overview
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Nephrons are the functional unit of the kidney

• Nephron
• Glomerulus
• Proximal convoluted tubule
• Loop of Henle
• Distal convoluted tubule
• Uriniferous Tubule
• Nephron
• Collecting tubule duct

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Cortical vs. juxtamedullary nephrons
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Glomerulus
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Renal corpuscle
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Podocytes team up to make filtration slits
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Building an ultrafiltration barrier
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Getting the scale correct, as might be seen in an
EM photograph
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When a filter gets dirty it must be cleaned-
mesangial cells are the janitors
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Proximal distal convoluted tubules
Renal corpuscle
Medullary ray
Collecting tubule
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Proximal tubule cells
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The thin limb of the loop of Henle
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Thin limbs of the loop of Henle
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Histologically the ascending thick limb the
distal convoluted tubules are the same
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Collecting tubule
Thick
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Distal convoluted (shorter)
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Glomerulus
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Collecting tubules
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How about thick and thin limbs
Collecting tubules
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Collecting duct
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Collecting ducts (of Bellini)
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Ducts exiting at the area cribrosa on the papilla
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Arteries, veins lobes
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More vasculature lobules
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Kidney capillaries
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Large lobar artery entering from medulla
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Intermediate size arcuate at border of cortex
and medulla
Cortex with Corpuscles Convoluted tubes
Medulla with straight tubes
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Interlobular (running up in middle of
lobule between corpuscles
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Minor calyx
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Transitional epithelia
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Dome cells
Calyx epithelia
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Ureter
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Circular smooth muscle
Longitudinal smooth muscle
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Dome cells
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Urinary Bladder
Transitional epithelium
Bundles of smooth muscle
Dense irregular CT
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Transitional epithelia changes depending on how
full the urinary bladder is
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Transitional epithelia membrane
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