P1254325912KdJiv

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GP lab II
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Cell Death and Necrosis
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Necrosis

• cell death due to injury
• nuclear changes
• pyknosis karyorrhexis karyolysis

normal cell
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Necrosis

• Coagulative necrosis
• Liquefactive necrosis
• Caseous necrosis

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Coagulative Necrosis

• causes
• occlusion of arterial supply
• tissue architecture and
• cell outlines
• loss of nucleus

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Liquefactive Necrosis

• causes
• bacterial infection
• loss of tissue architecture and cell outlines
• PMN, pus cell, cell debris

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Caseous Necrosis

• Tuberculosis
• homogeneous pink area
• epithelioid cell, langhans giant cell,
  lymphocyte

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