The Status and Future of Integrative and Organ Systems Sciences October 20

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The Status and Future of Integrative and Organ
Systems SciencesOctober 20 21, 2002Bethesda,
MD

• Sponsored by APS and ASPET
• Co-sponsors Burroughs Wellcome Fund
• Merck Research Laboratories

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Definitions

• Reductionist approaches are aimed at identifying
  molecular and cellular events, studied in
  purified form or in isolated systems and
  including genomics, proteomics, biochemistry and
  cell biology
• Integrative and Organ Systems approaches are
  aimed at understanding how intact biological
  systems function at the level of whole animals,
  organs and organ systems (but not in the clinic).

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Life Sciences Research Office(LSRO)

• Michael Falk
• Executive Director

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Mission

• To benefit society by evaluating biological
  information and scientific opinion for the public
  and private sectors

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Steering Committee

• James R. Bloedel
• Joseph R. Haywood
• D. Euan MacIntyre
• Peter C. Preusch
• James H. Woods
• Edward J. Zambraski

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HGS Annual Reports

• Founded in 1992 leader in the discovery of
  human and microbial genes
• 1995 success in turning our leadership in gene
  discovery into leadership in the creation of
  proprietary pharmaceutical products
• 1997 year of change for our company, as we
  began to implement clinical development of our
  own drugs
• 1998 significant progress in its ongoing
  transition to a fully integrated
  biopharmaceutical company that discovers,
  develops, manufactures and markets
• 2000 genomics found only once