Learning objectives

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Learning objectives
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Table 3.1 Development of the human organs during
gestation
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Figure 3.1 The components of maternal weight gain
during pregnancy.
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Table 3.2 Optimal weight gain for women in
pregnancy is dependent up on their pre-pregnancy
BMI
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Figure 3.3 The role of GLUT4 in glucose
transport. GLUT4 translocation is a key step in
movement of glucose across cell membranes. In
pregnancy, the formation of IRS-1PI3-K
complexes is inhibited, leading to insulin
resistance.
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Figure 3.4 The biosynthesis of long-chain
polyunsaturated fatty acids from the essential
fatty acids.
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Figure 3.5 The metabolism of vitamin D.
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Table 3.3 Risk factors for preterm delivery
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Research Highlight 3 Advice to reduce caffeine
intake in pregnancy
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Figure 3.6 The pathophysiology of PE.
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Figure 3.7 The temporal association between
symptoms of nausea and vomiting in pregnancy and
concentrations of hCG.
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Figure 3.8 NVP is associated with reduced risk of
preterm delivery. Three hundred pregnant women
were questioned about symptoms of NVP in the
first trimester of pregnancy and the outcome of
pregnancy was followed up. Women who reported no
NVP symptoms were significantly more likely to
give birth prior to 37 weeks gestation. (Source
Langley-Evans and Langley-Evans, unpublished
observations.)
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Figure 3.9 GDM is a condition of maternal insulin
resistance. Maternal insulin resistance drives
glucose across the placenta to the fetal tissues.
The ensuing increase in fetal insulin secretion
drives excessive fetal growth and leads to LGA.
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Summary Box 3
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Self-Assessment Questions