Title: Interconception Care Program Recruitment Strategies
1Welcome
Interconception Care Program Recruitment
Strategies
2Housekeeping
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this call. Phones will be muted during the
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well keep track of them. - Slides, speaker bios and speaker contact info are
available at www.everywomansoutheast.org.
3Acknowledgements
- March of Dimes
- Lori Reeves for TA with todays webinar.
- The W.K. Kellogg Foundation
- Every Woman Southeast Volunteers
- Our Speakers
4What is Every Woman Southeast?
- A coalition of leaders in Alabama, Florida,
Georgia, Kentucky, Louisiana, Mississippi, North
Carolina, South Carolina and Tennessee to working
together to build multi-state, multi-layered
partnerships to improve the health of women and
infants in the Southeast.
5 www.EveryWomanSoutheast.org
6Our Blog
7Monthly E-Newsletter
8Join Your State Team
- We have 9 state teams one for each state.
- Find your team lead by clicking on your state
webpage on our website. - Contact the lead and connect. This is a great
way to link up with the latest resources and
opportunities on preconception health.
9Todays Webinar
- Interconception Care Program Recruitment and
Retention Strategies - October 24, 2012
10Why This Topic?
- Reducing risks indicated by a previous adverse
pregnancy outcome is a top goal of the National
Preconception Health and Health Care Initiative - In the SE 3 states have demonstration projects
to provide interconception care to high risk
women - Limited information about best practices in
serving this population
11Objectives
- Describe current efforts to promote
interconception health care for high risk women - Describe how to overcome at least one challenge
to recruitment - Describe at least two strategies that improved
recruitment and retention - Discuss ways that interested groups can continue
to connect on this issue.
12Speakers
- Sarah Verbiest, DrPH, MSW, MPH
- Dean Coonrod, MD, MPH
- Jennifer Culhane, PhD, MPH
- Anne Dunlop, MD, MPH
- Betsy Bledsoe-Mansori, PhD, Mphil, MSW
- Carol Brady, MPH
13The Postpartum Plus Prevention Program in NC
- Sarah Verbiest, DrPH, MSW, MPH
- Executive Director
- UNC Center for Maternal and Infant Health
- Director
- Every Woman Southeast Coalition
14The Postpartum Plus Prevention Program (P4)
- Designed to increase knowledge about how to
provide health and wellness services to mothers
of medically fragile infants. - Services postpartum visit, a wellness kit at 3
months, and contact with a nurse midwife at 3, 6,
9, 12 and 18 months postpartum. - P4 also provided onsite medical care to any woman
in the NICU who requested help.
15Enrollment
- Women were approached for enrollment by a nurse
midwife while their infant was in the NICU. We
didnt have anyone decline participation. - A convenience sample of 44 mothers was recruited
from the Newborn Intensive Care Unit at UNC. - Nearly all (87) of the women had received a
medical service from the nurse midwife prior to
being recruited into the study.
16What We Found
- Almost every mother (97) returned to UNC
post-discharge for infant follow-up. - Initial expectations were that mothers would only
be reachable by phone but the majority of
mothers also received in-person support. - Mothers were open to talking with the nurse
midwife during pediatric visits for their infant.
17Contacts
- We anticipated about 220 total contacts with the
women in the study. We had 645 contacts! - The nurse midwife had an average of 15 contacts
with each mother. The number of contacts per
woman ranged from 6 to 42 the lowest number was
still above our expectation. - One third of the women went through a period of
time where they had weekly contact with the nurse
midwife usually due to a crisis in their babys
health.
18Content
- Almost all contacts began with a mother-led
conversation about the infants health. - The nurse midwife introduced wellness messages in
the context of the impact of the mothers health
on the well-being of her infant. - Mothers needed support for nonmedical issues such
as relationship with the infants father,
poverty, employment, and loss/grieving.
19Conclusions
- Mothers of medically fragile infants are
receptive to tailored wellness messages when
provided along with clinical care for themselves
and their baby. - The NICU provides a key opportunity for initial
outreach to high-risk mothers. - Telephonic support is a good option for providing
services and support, especially when paired with
in-person contact through pediatric services to
the infant.
20Conclusions
- Mothers capacity to attend to their own health
and wellness needs is linked to the immediate
health status of their infant. - Easy access to health care services from a
professional they trusted was very important. - Innovative partnerships between OB/GYN and NICU
follow-up clinics should be considered to best
serve both high-risk mothers and infants.
21Arizonas Internatal Clinic
- Dean V Coonrod, MD-MPH
- Chair, Department of Ob/Gyn
- Maricopa Integrated Health System / District
Medical Group - University of Arizona College of Medicine -
Phoenix
22Context
23Preconception vs Interconception vs Internatal
Care
interconception
preconception care
pregnancy
no more kids!
internatal care
24Program Eligibility
- Index pregnancy
- Preterm birth 35 weeks or less
- Early pregnancy loss 15 weeks and more
- Stillbirth
- Low birthweight
- Prolonged NICU stay
- Initially 3 days now 5 days
- Not permanently sterilized
25Schedule of Visits
- 2 weeks
- Breastfeeding, review family planning
- 6 weeks
- Standard postpartum visit
- 6 months
- 12 months
- Yearly thereafter
- Preconception visit
26Our Visits
- Seen by care coordinator
- Introduce program
- Edinburg Postpartum Depression scale
- 6-week intake form
- Go over education goals for nutrition,
exercise, dental care, folate - Psychosocial support, stress management
27Our Visits
- Seen by physician
- Reason for visit
- Index pregnancy reviewed
- Neonatal status
- Breast feeding / back to sleep
- Prior ob history
- Reproductive life plan, contraception
- Gyn, STI history / screening
- PMH / PSH / Dental care
Underlined Done at all visits
28Our Visits
- Infection / immunization
- TB, Rubella, Tdap (pertusis), varicela, influenza
- Nutrition / exercise
- Anemia, food security, BMI, folate, exercise
(type / amount) - Meds / allergies
- Habits / Social / Exposures
- Tobacco, alcohol, drugs, DV, work, environmental
exposures - Behavioral health
- EPDS, other mental health, eating disorders
- Physical exam
- Weight (BMI), BP etc
- Problem focused exam
29Our Project Patients End of 2010
- 696 approached
- 142 had a visit
- 90 Latina
- 71 seen for clinical services in the last 6
months and are considered active - 71 have relocated or have been lost to follow up
30Final Results (n102 women)
- In program for 12 to 18 months
- Of those pregnant at least 12 month interval
- Of those pregnant with first trimester care
- Of those pregnant, tob, ETOH, drug free
- Using contraception (if indicated)
- On folate
- Regular exercise (30 min 5 days a week)
- Normal BMI
- Those with oral health needs who have treatment
- Those with mental health needs who have treatment
- 64
- 40
- 87
- 100
- 88
- 61
- 23
- 26
- 20
- 100
31Follow Up Data
Baseline 6-month 12-month
Health is Excellent 46 55 70
Regular Exercise 23 76 70
Very Interested in Getting Preconception Information 53 76 69
Alcohol Can Effect Fetus 73 83 94
Watchful About Eating Fish 48 77 88
32Lessons Learned
- Care coordination key
- Mothers / families after a pregnancy ending in
stillbirth very interested - Patients with preterm birth have varying levels
of interest - No show rate a significant problem
- Interval of visits often dictated by family
planning or other issues / mental health - Usually more frequent than the idealized one
- TLC is always provided and likely of benefit
33(No Transcript)
34Thanks to our partners and funders
- March of Dimes
- Maricopa Dept of Public Health
- ADHS
- BHS
- Mercy Care Plan
- University Health Plan
- Az Public Health Association
- Mayo Clinic Family Medicine
- Maricopa Integrated Health System
- Ob/Gyn
- MFM
- Family Medicine
- Ambulatory
- Social Work
- Southwest Human Development
- St Lukes Health Initiatives
- AHCCCS
35Questions?
- Dean_Coonrod_at_DMGAZ.org
36The Philadelphia Collaborative Preterm
Prevention Project
- Jennifer F. Culhane MPH, PhD
37The Study
- Before discharge from the post partum hospital
stay - Consent including access to medical records
- Conduct survey
- Randomization
- Smoking intervention begins
- Schedule 1st postpartum visit (1 month)
38Postpartum Study Visits
- When 1, 6, 12, 18, and 24 months postpartum
- Or, at 20 weeks gestation of the subsequent
pregnancy
39Postpartum Study Visits
- Survey
- Periodontal exam (1, 12 and 24 months only)
- Vaginal fluid (self collection)
- Blood
- Urine
- Anthropometric measurements
- Blood pressure
- Transportation, flexible hours, childcare,
barriers eliminated
40Intervention Arm
- Evaluated and offered treatment for
- Depression
- Periodontal disease
- Urogenital tract infections
- Abnormal BMI
- Housing instability/inadequacy
- Smoking
- Literacy
41Recruitment Rate
77.7
Figure 2. Webb, et al. BMC Medical Research
Methodology, 2010, 1088
42 Retention/Data Capture Rates for Study Population
Randomization Intervention Group Control Total
First Post Partum Assessment 83.5 76.0 80.0
Second Post Partum Assessment 67.6 57.5 64.6
Third Post Partum Assessment 60.0 48.9 54.4
Fourth Post Partum Assessment 54.2 46.3 50.3
Fifth Post Partum Assessment 47.3 40.8 43.6
43Strategies to Improve Retentions
- Two full-time staff dedicated to cohort
maintenance - Provided transportation - either tokens or cab
pick up - Evening and weekend hours
- Child care and food provided
- If required visit conducted at participant's
home - Clinic had washing machines and dryers
- Staff required to be courteous and totally
participant -focused - Compensation for time
44Risk Factor Prevalence, Acceptance Rates and
Rates of Minimal Participation in PCPP
Intervention Arms
45Strategies to Improve Participation in
Interventions
- Phone medicine for depression care available
- Staff accompany participants to dentist
- Provide valium for dental visits
- Smoking intervention conducted in particpants
home - Medicines delivered to particpants home
- Food and caloric supplements delivered to
participant's home
46Selected Findings
- Exposures associated with adverse outcomes are
moderately prevalent and co-occur. - There is a wide range of participation across
interventions- even with every traditional
barrier to care addressed. - Volunteering for treatment is MUCH different than
random assignment to treatment- people who really
need the intervention may not seek care
47Important Research Questions
- Why dont some women avail themselves of care?
- Not just traditional barriers to care
- Complex decision making that may seem irrational
to providers but may make perfect sense in
certain contexts- what are those contexts?
48Important Research Questions
- RHIME factors (Racism, Housing challenges,
Insufficient resources, Multiple burdens and
Emergencies) play a role in womens everyday
lives and influence care participation - We need to become aware of, document and address
the ways various institutional structures, rules
and ways of doing business create additional
burdens for already stressed women
49Summary
- Truly at risk women may not participate
- Even if an intervention works it may not be
successfully implemented- what do we mean by
works? - More research needed to understand complex
barriers to participation
50- The Interpregnancy Care Program
- Overview of Engagement Strategy
- For Women Who Recently Delivered
- A Very-Low-Birthweight Infant
- Anne L. Dunlop, MD, MPH
- October 24, 2012
51IPC Participants
- Eligibility African-American women who
qualified for indigent care and delivered a VLBW
infant at Grady Memorial Hospital (GMH) during
the feasibility phase (11/2003 through 3/2004). - Recruitment/Enrollment
- 29 women enrolled (of 38 eligible)
- 24-months of follow-up complete 3/2006.
52IPC Intervention Package
- Definition of an individualized IPC plan to
address 7 areas epidemiologically linked to low
birth weight/preterm delivery - Reproductive planning (assistance in achieving
intendedness and spacing) - Prevention, screening and treatment for
sexually-transmitted infections - Micronutrient supplementation
screening/treatment for nutritional deficiencies - Prevention, screening and treatment for
periodontal disease - Management of chronic disease
- Treatment and referral for substance abuse
- Screening and treatment for depression,
psychosocial stressors, domestic violence - Provision of health and dental services in
accordance with the IPC plan for 24 months - Community outreach via a trained Resource Mother.
53Provision of IPC
- Contact with a multidisciplinary team
- Family nurse practitioner, family physician,
periodontist, nurse case manager, social
worker, and Resource Mother - Initial contact with nurse case manager followed
by Resource Mother during the delivery
hospitalization. - Primary care visits occurred every 1 -3 months
(dependent upon extent of health problems) in a
group setting with integration of group
educational experiences according to the
Centering Pregnancy Model of prenatal care - Home visits and telephone contact by the Resource
Mother monthly to address psychosocial issues.
54Participation in IPC
- 21/29 (72) actively participated
- 8/29 (28) not actively participated
- 2 moved out of state
- 3 electively disenrolled (2 prior to 1st IPC
visit 1 after single visit) - 3 become lost to follow-up (2 prior to 1st IPC
visit 1 after single visit).
55Impact of IPC Social Outcomes (Education)
- Educational Attainment
- 18/21 (85.7) active participants without h.s
diploma or GED at study entry - Of those 18 without diploma or GED, 13/18 (72.2)
were assisted in earning diploma or GED during
the study - 8/18 earned h.s. diploma or GED
- 5/18 enrolled in G.E.D. training program,
but did not
complete the program.
56Impact of IPC Social Outcomes (Training)
- Other Training
- In addition to GED, 4 participants completed
technical training (2 computer literacy, 2
medical assistance) - In addition to h.s. diploma, 1 participant
completed Upward Bounds (college preparatory
program) - A participant with a h.s. diploma completed
technical training (administrative assistance).
57Impact of IPC Social Outcomes (Housing)
- Housing Acquisition
- 14/21 active participants with inadequate
(crowded, dirty, unsafe) housing or homeless at
study entry - Of those 14 who were homeless or with inadequate
housing, 11/14 assisted in finding adequate
housing.
58Cost of IPC per Participant Full 24 months
- Health care
- Mean charges 2,397 (median 2,104)
- Mean visits 7 (median 6)
- Mean cost per visit 342 (median 350)
- Resource mother outreach
- Estimated 1,800
Total Program Cost per Participant per 24-Months
4,197
59Cost Analysis
- The 29 enrolled women received 24-months of IPC
at 4,197 each, and delivered 1 LBW infant
(initial hospitalization 55,576) conceived
within 18-months of the index VLBW - Cost of program 29 x 4,197 121,713
- Cost of LBW infant 55,576
-
177,289 - Based on the historical control cohort, we
expected 5 LBW infants to be conceived within
18-months of the index VLBW - Cost of LBW infants 5 x 55,576 277,880
- Net savings 100,591
60Translation of IPC
- Planning for Healthy Babies Georgia Medicaid
Waiver, beginning January 2011, will expand
Medicaid coverage for specific reproductive
health services to Georgia women 200 FPL - Family planning services (broadly) for all women
of reproductive age - Interconception primary care, case management,
and resource mother support for all women who
deliver a VLBW infant after Jan 1, 2011. - Services to be delivered through the Georgia
Medicaid CMOs - Amerigroup, Peach State, WellCare
- Small trial of NICU-based engagement in 3 metro
area NICUs
61Engaging and Retaining Difficult to Reach
Mothers in Treatment Services Overview of a
Brief Intervention.Betsy (Sarah E.)
Bledsoe-Mansori, PhD, MPhil, MSWAssistant
Professor School of Social WorkUniversity of
North Carolina at Chapel HillOctober 24, 2012
62Acknowledgements
- Pregnant women and adolescents from Pittsburgh,
PA Seattle and King County, WA and Alamance and
Wake Counties, NC who participated in the
research studies supporting this work. - Funding sources -- National Institute of Mental
Health, National Institutes of Health, Horizons
Foundation, Seattle, WA, Jane H. Pfouts Research
Grant, Armfield-Reeves Innovation Fund,
University of North Carolina Program on Ethnicity
Culture and Health Outcomes, University of North
Carolina - Co-investigator s and collaborators Nancy
Grote, PhD Holly Swartz, MD Allan Zuckoff, PhD
Ellen Frank, PhD Katherine Wisner, MD Wayne
Katon, MD Carol Anderson, PhD Sharon Geibel,
MSW
63An Ecological Model of Barriers to Treatment
Engagement and Retention
Distal Influences ----gt Proximal Influences
----gt Rx Adherence ----gt Rx
Outcomes
Community Barriers Helping
System Barriers violence, safety concerns
bias or cultural insensitivity in
lack of support services
environment, procedures, providers unemployment
poverty lack of
evidence-based treatments lack of access to M.H.
services lack of diversity in clients
staff
provider overload and
burn-out
Social Network
Barriers Client Barriers
negative attitudes toward RX
practical- time, financial, transportation,
childcare social network strain
psychological - stigma, low
energy,
negative
RX experiences previous or current trauma
cultural womens view of
depression multiple stressors
culture of poverty
culture of race/ethnicity/nationality
64Barriers to Care
- Practical Do I have time? Can I get there? Can
I afford it? - Psychological Can I trust my therapist? Can
she/he really understand me and help me? - Cultural Will treatment be relevant to my
needs, goals, values, preferences and practices?
65Practical Barriers to Care
- Costs
- 40 African Americans and 52 Hispanics lack
health insurance in the US (US Census Bureau,
2003) - Access
- Inconvenient or inaccessible clinic locations
- Limited clinic hours
- Transportation problems
- Competing Obligations
- Child care and social network
- Loss of pay for missing work
- Time in dealing with chronic stressors
66Psychological Barriers to Care
- STIGMA
- I dont want to be that person to get the
medication and be called DEPRESSED my sister
had to live with that label and everyone
avoided her and treated her like it was her
fault. - NEGATIVE EXPERIENCES WITH SERVICE PROVIDERS
- I didnt want the therapist to report my
depression to child protective services because
they might take my baby away. I felt betrayed. - CHILDHOOD TRAUMA AND LACK OF TRUST
- Greater risk of insecure attachment and lack of
trusting others (Mickelson et al., 1997) - Implications for seeking treatment go-it-alone
attitude poor collaboration, missed
appointments requires extensive outreach
67Cultural Barriers to Care
- CULTURE OF POVERTY
- My therapist seemed overwhelmed by all my
practical problems, so how could she help me? - CULTURE OF RACE/ETHNICITY/NATIONALITY
- No it doesnt matter
- Sitting in front of a white therapist isnt
necessarily like she thinks she is better than
me, BUT there are some white people who think
they can look down on you and show favoritism to
people of their nature and culture and treat you
any kind of way.
68Development of an Engagement StrategyBefore
Treatment Begins
- To deal with practical, psychological, and
cultural barriers to care and ambivalence about
going for depression treatment - Integration of two theoretical approaches
- Ethnographic interviewing
- Motivational interviewing
69Ethnographic Interviewing (EI)
- A method of eliciting information designed to
help the interviewer understand the ideas,
values, and patterns of behavior of members of
another culture without bias (Schensul, Schensul,
LeCompte, 1999) - Anthropological Uses
- Foreign cultures
- Sub-cultures
-
70Motivational Interviewing (MI)
- Client-centered, goal-oriented method for
enhancing a persons own motivation to change by
working with and resolving ambivalence (Miller
Rollnick, 2002)
71Principles of Engagement (Grote, Zuckoff,
Swartz, Bledsoe, Geibel, 2007)
- 1) Work to understand the perspectives and values
of the woman without bias or agenda - 2) Adopt a one-down position as learner
- 3) Help the woman to feel safe to tell her story
(whats bothering her) without fear of judgment - 4) Find out how the depression or stress is
interfering with what is important to her this
primary motivator for change!
72Principles of Engagement
- 5) Affirm the womans strengths and coping
capacities (e.g., resilience, knowledge,
spirituality, family) - 6) Obtain permission before giving information or
advice - 7) Provide psychoeducation about the problem and
effective treatments and elicit the womans
reaction - 8) Identify pros and cons about getting treatment
(ambivalence) pull for the negatives - 9) Express empathy, especially for the reasons
against seeking treatment (as well as reasons for
seeking treatment)
73Principles of Engagement
- 10) Foster personal choice and control ( Its up
to you!) - 11) Problem-solve all the barriers with the woman
- 12) If the woman commits, collaborate with him or
her to make the connection with mental health
services - 13) Offer hope, acceptance of ambivalence,
affirmation - 14) Leave the door open, if she does not commit
74Engagement Session 5 components(Unpublished
manual, Zuckoff, Swartz, Grote, Bledsoe
Speilvogle)
- Total time 50-60 minutes -- These components can
be used separately if time is limited or repeated
as needed. - 1) Getting the story
- 2) Past efforts at coping and attitudes toward
treatment - 3) Feedback and psychoeducation
- 4) Addressing barriers to care
- 5) Eliciting commitment and planning for
treatment engagement
75Engagement Component 1 The Story
- Introduce session
- During this time I would like to get to know you
better how you see whats bothering you,
whether you want help, and if so, what you would
want out of treatment services. - How have you been feeling lately and how is this
interfering with whats important to you? - Explore the Story
- A. Problem understanding of the womans
view of her depression/stress how it is
interfering with clients life - B. Context social context of the problem
acute stressors (stressful life events
pregnancy) and chronic stressors (like poverty) - C. Summary empathically summarize clients
story highlight concerns and wishes identify
and affirm strengths
76Engagement Component 2Treatment History Hopes
for Treatment
- History of the problem ask about past or current
efforts to cope with the problem (e.g. spiritual
beliefs, family, inspirational people) identify
and affirm strengths empathically summarize - Treatment history ask about clients or family
members experiences with or ideas about
treatment get both positive and negative ask
about experiences with social agencies/health
care providers - Treatment hopes/expectations
- What would you like to be doing if treatment
worked? - What do you want/not want in treatment or in a
therapist? - Does race/ethnicity matter?
- Empathically summarize hopes and fears for
treatment, capturing the womans ambivalence
while highlighting hope
77Engagement Session Component 3Feedback and
Psychoeducation
- Feedback
- A. Elicit Would it be OK if I shared some of
the results from the questionnaire you filled
out? or my ideas about what youre struggling
with? - B. Provide symptom severity, consequences of
depression/stress - C. Elicit What do you make of this? How does
this sound? - Psychoeducation
- A. Elicit What is your view of depression?
Would it be OK if I gave you some information
about it and treatment options? - B. Provide information about depression and
treatment - C. Elicit How does this sound to you? Does
this make sense?
78Engagement Session Component 4Problem-solving
the Barriers to Care
- Practical What might make it hard to come even
if you wanted to? Transportation? Childcare?
Scheduling? Finances? - Psychological Beyond these practical concerns,
what else might keep you from coming? Keep
asking, What else? - Negative attitudes about treatment? The burden
of dealing with the symptoms of the problem?
Guilt about taking time for self? Concerns that
CPS might become involved? Doubts about whether
treatment will help? Perceived stigma from
family and friends? - Cultural How is treatment viewed in your
family or community? - 1) How can treatment help me with getting a
job, house, food, etc.? - 2) Preferred community approaches for treatment
(e.g., church)? - 3) Therapist differences in race, class, gender,
age, nationality? - therapist would judge, not understand, act
disrespectful, not care - therapist does not know how to cope with clients
problems no experience
79Engagement Session Component 5
Elicit Commitment
- Grand Summary summarize womans story,
ambivalence, barriers and solutions highlight
her change talk I cant take this anymore. - Change Plan outline next steps, e.g., scheduling
an appointment, number of treatment sessions - Elicit Commitment What would you like to do?
Does this sound right for you? - Leave Door Open Its fine if you want to think
about it, you can give me a call. - Instill Hope Affirm womans participation in the
session and the strengths client brings to
treatment express optimism about treatment
80Randomized Study of Pregnant, Depressed Women
Rx Engagement and Retention (Grote, Zuckoff, et
al., 2007)
plt.001
plt.001
plt.001
Less than 1/3 of phone intakes attend 1 Rx
session in community mental settings Typical
number of Rx sessions attended in community
mental health 1
81 with Major Depression Diagnoses
92
79
42
30
5
0
Pre Post-Rx plt.05 Pre F/U plt.05
82Feasibility Study of Depressed Pregnant
Adolescents (Bledsoe, Wike, Olarte, et al, 2010)
88 of eligible adolescents entered and 93
completed.
83More Research on Engagement Session
- PREMIUM (Program for Effective Mental Health
Interventions in Under-resourced Health Systems)
in Goa, India funded by the Wellcome Trust, UK
(Vikram Patel, PI) - Patient Navigation for Depressed Mothers in Head
Start in Boston, MA- An Engagement Strategy
funded by NIMH (Michael Silverstein, PI)
84Questions Answers
- Facilitated by
- Amy Mullenix
- Every Woman Southeast co-chair
- Please submit your questions via chat. Feel free
to contact speakers after the webinar with any
additional questions.
85Join us!
- Join our listserv http//www.surveymonkey.com/s/FQ
S2P3W - Bookmark our website www.everywomansoutheast.org
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and Pin our page! - Contact Sarah at sarahv_at_med.unc.edu or
919-843-7865
86A woman's health is her capital. Harriet Beecher
Stowe