ACCOMPLISHMENTS

1
Oxidation Resistant Ti-6Al-4V-SiC Composite
Materials by Ion-Beam Processing
Small Business Innovation Research
Spire Corporation Bedford, MA
INNOVATION
Developed silver-based antimicrobial coatings for
reducing bacterial adhesion and proliferation on
medical devices.

• ACCOMPLISHMENTS
• Demonstrated significant reduction in bacterial
  growth and colonization on treated medical
  device surfaces
• COMMERCIALIZATION
• Foundations of the antimicrobial coating
  technology were developed under NIH and NSF
  grants and contracts. Continued work with NIH
  includes development of silver-based
  antimicrobial coatings for additional medical
  device applications.
• Earlier, the NASA SBIR Phase I contract
  contributed to the establishment of Spires ion
  beam assisted deposition (IBAD) processing
  capabilities, upon which the antimicrobial
  coating technology is based
• Spire currently processes over ten thousand
  medical device components annually, resulting in
  several hundred thousand dollars in annual
  revenues
• Broad medical device applications, i.e. various
  catheters and other implantable medical devices,
  are being pursued with significant growth
  expected over the next few years
• Increase in employment of 4 people

980578A
Antimicrobial IBAD silver coated medical device
components

• GOVERNMENT/SCIENCE APPLICATIONS
• Potential uses in limiting device-related
  infection for military applications/personnel
• St. Jude Medical is currently using the
  Antimicrobial Coatings on prosthetic
  mechanical heart valve suture rings

Lewis Research Center Technical Area -
Materials 3-011
1987 Phase I, NAS3-25326, 6/98 NASA Contact -
James Smialek Company Contact - Ron Scharlack