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Purposes of Research

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Title: Selection Bias and the Importance of Theory Author: Dahlia Remler Last modified by: Dahlia Remler Created Date: 1/25/2001 12:43:28 PM Document presentation format – PowerPoint PPT presentation

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Title: Purposes of Research


1
Purposes of Research
  • Purposes of Research
  • Exploration
  • Description
  • Explanation
  • Our focus
  • Evaluation
  • Explanation makes evaluation much better and
    easier, but evaluation can also be done without
    explanation
  • Examples from our teenage drug use study

2
Experiments and Evaluation Research
  • Experiments are the most direct way to address
    hypothesis testing, particularly for evaluations
  • We often cannot do experiments
  • Experiments also have weaknesses
  • Understanding how one would do an experiment to
    address a research question is critical to
    designing good non-experimental research

3
Experiments
  • Experiments consist of
  • (1) Taking Action
  • (2) Observing Consequences
  • Experiments are useful for testing hypotheses
  • Hypothesis Example Dads spending more time with
    teenagers reduces teenage drug use
  • Sub-hypothesis Example Time reduces drug usage
    through improving the father-teenager relationship

4
Advantage of Experiments
  • Why will an experiment answer our question about
    Dads time and teenage drug use better than the
    survey (observational data) did?
  • What if teenage drug usage causes poor
    relationships with fathers?
  • What if drug usage and poor relationships are
    both caused by low socioeconomic status? What if
    both are caused by genetically-based low
    self-esteem?

5
Advantage of Experiments
  • Experiments allow us to disentangle correlation
    and causation
  • Experiments allow us to directly observe
    causation

6
Classical Experiments
  • Cleanest and easiest in the natural sciences
  • Independent and Dependent Variables
  • Pre-testing and Post-testing
  • Experimental and Control Groups

7
Independent and Dependent Variables
  • An experiment looks at the effect of an
    independent variable on a dependent variable.
  • The independent variable is the cause.
  • The dependent variable is the effect.
  • Example
  • Dependent variable teenage drug usage
  • Independent variable time spent by Dads with
    teenagers

8
Independent and Dependent Variables Issues
  • The meaning of independent variable and dependent
    variables is clear in experiments, by design.
    Things are less clear with non-experimental data
    analysis.
  • Dependent and Independent variables must be
    operationalized. The actual measures we have may
    be poor proxies for what we want to know.
  • Example
  • Self-reported drug use vs. actual drug use
  • What constitutes drug use? Ever trying?

9
Post-test vs. Pre-test
Pre-test
Post-test
The Treatment Change Independent
Variable (Experimental Stimulus)
Measure Dependent Variable
Measure Dependent Variable
How has dependent variable changed?
10
Problems with simple pre-post comparison
  • The simple pre-test and post-test comparison
    interpretation assumes that the change in
    dependent variable is due to the change in
    independent variable, the treatment.
  • What else could cause a change in dependent
    variable?
  • Response to attention of observers Hawthorne
    Effect
  • Changes which would have happened anyway, due to
    other causes

11
Treatment and Control Groups
  • Treatment Group Those receiving change in
    independent variable (experimental stimulus),
    the treatment.
  • Control Group Those who do not receive change in
    independent variable, the treatment.
  • Attribute difference (between treatment and
    control) in differences (pre- and post-) to the
    treatment.

12
Comparability of Treatment and Control Groups
  • Counterfactual what would have happened to the
    treatment group if they had not received the
    treatment.
  • The control group is supposed to tell us about
    the counterfactual.
  • The control group should be comparable to the
    treatment group in every way which matters
  • starting dependent variable
  • relevant observable variables
  • relevant unobservable variables

13
Treatment-Control Design
Treatment Group
Control Group
Measure Dependent Variable
Measure Dependent Variable
Compare same?
Administer Treatment
Compare different?
Remeasure Dependent Variable
Remeasure Dependent Variable
14
Difference in Differences
15
Example Share of Teenagers Using Drugs
16
Why does the control change?
  • Placebo and Hawthorne Effects Effect of being
    studied, having attention paid, thinking that you
    are being helped, etc.
  • General Trends Affecting Everyone e.g.,
    improving economy, anti-drug campaigns on TV

17
Blind Experiments
  • To make sure that a treatment effect is real and
    not due to thinking that you are going to be
    helped, experiments, particularly drug trials are
    often done blindly, so that people do not know if
    they are in the treatment or control group.
  • This is now being done for some surgical trials,
    amid great controversy.

18
Double-Blind Experiments
  • Sometimes researchers will treat or evaluate the
    treatment and control groups differently,
    frequently unconsciously. To avoid this problem,
    studies, particularly drug trials are done
    double-blind, i.e. without the researcher
    knowing who is treatment and who is control.

19
Methods of Ensuring Treatment-Control
Comparability
  • Randomization (the gold standard)
  • Sampling from a given population subjects are
    randomly allocated to treatment and control
    groups
  • No systematic differences between treatment and
    control
  • What if people refuse the treatment?
  • Lack of comparability due to chance variation gt
    Sample-size issues
  • Matching
  • Make the treatment and control groups as alike as
    possible in observable characteristics

20
Randomization over Matching?
  • Matching on particular variables is difficult
    because you do not know which ones are important
  • Statistics assume randomization
  • Can combine through stratification-- to be
    covered after sampling

21
Generalizability
  • How are experiment subjects chosen?
  • In medical trials, often those with no other hope
    or those who physicians think are most likely to
    benefit
  • For statistical reasons, the groups are made as
    homogeneous as possible-- although recent
    controversy has prompted inclusion of women and
    minorities
  • But we want results which are applicable
    (generalizable) to a much more general
    population.

22
Problems with Experiments
  • Generalizability
  • Ethical Considerations
  • Expense
  • Samples too small
  • General Equilibrium Effects Its different if
    the whole system changes
  • Utterly impossible to do

23
Selection Bias and the Importance of Theory
Dependent Variable Teen Drug Use
Independent Variable Dad Time with Teen
More Time Treatment
No Drug Use
Drug Use
Less Time Control
Why do some Dads spend more time with their teens
than other Dads?
Could the same factors influence drug usage?
24
Selection Bias and the Importance of Theory
Dependent Variable Teen Drug Use
Independent Variable Dad Time with Teen
More Time Treatment
No Drug Use
___________ ___________
Drug Use
Less Time Control
Why do some Dads spend more time with their teens
than other Dads?
Could the same factors influence drug usage?
25
Selection Bias and the Importance of Theory
  • No ability to do randomized experiments
  • ?
  • Theory is very important to decide why
    treatment and controls differ
  • Are the same factors relevant in determining
    outcomes?

26
Exogeneity and Endogeneity
  • Exogenous Determined Outside the System
  • Endogenous Determined Inside the System
  • Depends on the Dependent Variable
  • Is time with Dad exogenous to Drug Usage?
  • If and only if drug usage does not cause change
    in time of Dad with Teen
  • If and only if factors that influence drug usage
    do not also influence time of Dad with Teen
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