Bio 342 Human Physiology

1
Bio 342Human Physiology

• Pick up an information form, complete it, and
  turn it in before leaving.

2
A physiologist asks

• How do things work in the human body?
• How is stability achieved?
• What are the causes and consequences of
  disruptions of stability?
• How can stability be restored?
• How do we know whats going on inside the body?
• How have things come to be the way they are?

3
Theme of this course

• Homeostasis

4
First Demonstration for Bio 342 Human Physiology

• Listen carefully to the music and to how it is
  interpreted
• Observe the human body in action during the
  performance of the piece
• Consider the activity of cells, tissues, and
  organs in the musician

5
Physiology in Action!Examples from the
performance
6
BIO 342 HUMAN PHYSIOLOGY

• PHYSIOLOGY The study of the function of cells,
  tissues, organs, and organ systems.
• THE TEXT Widmaier et al. 2008 (11th ed.)
• Chapter 2-5 review of other courses
• Using your textbook

7
General Course Objectives

• 1. To develop a basic understanding of the
  principles of physiology, with an emphasis on
  homeostatic mechanisms and negative feedback
  control.
• 2. To develop an appreciation for the
  experimental basis of our knowledge of
  physiology.
• 3. To sharpen laboratory skills with exercises
  that require forethought, planning, and
  refinement.

8
General Course Objectives

• 4. To organize and analyze information so as to
  develop critical thinking skills.
• 5. To write concisely in the form of scientific
  abstracts.
• 6. To communicate effectively in oral form.

9
The Syllabus (on the course websitehttp//webs.w
offord.edu/davisgr/bio342/)

• Office home phone numbers
• E-mail (davisgr_at_wofford.edu)
• Lecture topics by week
• Text chapters in parentheses
• Read in advance of lectures

10
A Website for this Course!

• Check daily.
• Get Study Questions and Powerpoint files via the
  website.

11
LABORATORIES

• 5-8 Computer setups, lt22 persons per lab
• 200 - 500 Mon (Davis) Tues 8-11
• 230 530 Tue (Moeller)
• 200 500 Wednesday (Nguyen)
• 230 530 Thursday (Nguyen)
• May shift topics due to availability of animals
• 1 Lab Report in the form of abstracts
• very concise, based on lab data
• Incorporate statistics
• With revision and resubmission
• No separate lab tests lecture tests include labs
• This weeks Lab Using live animals!

12
GRADING

• 3 lecture tests 60
• multiple choice (choose all correct answers)
• Some short answer
• Rarely fill in the blank
• Sometime create or complete graph or diagram
• discussion question(s)
• Cumulative final exam 20
• Other work 20
• Abstract 10
• 1 Question Quizzes (1QQs) 10

13
Honor Code

• All worked is to be pledged.
• Issues of plagiarism to be handled by the Honor
  Court

14
ODDS AND ENDS

• NO FOOD or DRINKS in Lab
• Possible limited lab swapping
• under special circumstance
• students arrange paired swap
• prior approval
• See Attendance webpage
• BE ON TIME, READY TO GET TO WORK
• DONT ASK ABOUT LENGTH OF LAB
• BE READY TO START ON TIME

15
Study Questions Quizzes

• Questions provided for each chapter (On the
  website!)
• Read the book and answer the questions PRIOR to
  class meeting
• Class time is used to deal with problematical
  topics and reinforce the major concepts
• Be ready for 1QQs

16
Study Questions Quizzes

• Rationale for this format
• Writing helps to consolidate memory and recall
• Greater effort results in better retention and
  understanding
• Students are not passive learners
• Able to cover more information

• Improve MCAT, DCAT and GRE scores

17
More stuff

• Be early or on time for lecture and lab
• Pay attention (no cell phones, email, Facebook,
  etc. during lecture or lab)

18
1st AssignmentPersonal Informationdue on Friday
19
Chapter 1 and parts of 16

• Tissues
• Organs
• Organ Systems
• Homeostasis
• Negative feedback
• Two detailed examples Thermoregulation and
  Glucose Homeostasis

20
Genetics Development
Cell Molecular
200
21
Cell types

• Neuron
• Hepatocyte
• Cardiac myofiber
• Septal cell (lung)
• Purkinje fiber (heart)
• Melanocyte
• Enteroendocrine cell
• Simple cuboidal cell of the proximal renal tubule

• Basal cell of stratum germinativum (skin)
• Endothelial cell
• Fibroblast
• Osteocyte
• Chondrocyte
• Acinar cell of pancreas
• Beta cell of Islet of Langerhans
• Schwann cell

22
More cell types

• Sertoli cell
• Leydig cell
• Hair cell (inner ear)
• Smooth myofiber of arteriole
• Mast cell
• Unilocular adipocyte
• Osteoblast
• Monocyte

• Langhans giant cell
• Megakaryocyte
• Satellite cell (ganglion)
• Myofibroblast in capsule of spleen
• Odontoblast
• Ameloblast
• Myoepithelial cell of salivary gland

23
Even More Cell Types

• Parietal cell
• Chief cell (stomach)
• Paneth cell
• Podocyte
• Juxtaglomerular cell
• Cell of the macula densa
• Chromaffin cell (adrenal medulla)

• Cell of the corona radiata
• Spermatogonia
• Granulosa lutein cell
• Secretory cell of the zona glomerulosa
• Secretory cell of the zonal fasciculata

24
Histology
25
Figure 01.01c
Anatomy
26
(No Transcript)
27
The Human BodyA Society of Cells

• Imagine you are a cell. Ask yourself
• How did I get here? 
• What do I do for myself? (What are my special
  characteristics and functions?) 
• What do I do for the person in whom I reside?
  (What are my contributions to the whole organism?
  To homeostasis?) 
• What do I need simply to survive?
• What do the other cells provide for me that I
  cannot obtain alone?
• What governs my actions? 
• How long will I live?
• Can I be replaced? If so, how?
• What would happen to the organism if I along with
  all the other cells of my type were to fail to
  function properly?

Choose a cell type from list, have answers ready
for class on Wednesday.
28
A physiologist asks

• How do things work in the human body?
• How is stability achieved?
• What are the causes and consequences of
  disruptions of stability?
• How can stability be restored?
• How do we know whats going on inside the body?
• How have things come to be the way they are?