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1
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2
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3
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4
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????????? ????????? ??????? ???????? ????????? ??????? ???????? ?????? ? ??????? ???????, ??p(Ds2 Dd2) /4 (??2), ??? D?????????? ???????
??????? ??????????? ??????? ?????? ??????? ??????????? ??????? ???????????? ??????, WCSA p (De2 Di2)/4 (??2) , ??? De, ??????? ??????? ? Di, ?????????? ??????? ? ????????  
???????????? (???????) ???????? ??????? ? ????? ???????????? (???????) ???????? ??????? ? ?????
??????????? ?????????? ???????????? (DC) ????????????? ????????? ??????? ??????????? ???????? ? ??????? ??????? ? ????? ?? ?????? ????????? ????????, DC ?A/A ?P (??? -1), ??? ?P ????????? ????????? ????????
??????????? ?????????? ???????????? (?C) ?????????? ????????? ??????? ??????????? ???????? ?????? ? ??????? ??????? ? ????? ?? ?????? ????????? ????????, ?? ?A/?P (?2???-1), ? ?P ????????? ????????? ????????
?????? ????????? ????????? ????????, ???????? DC ????????? ???????? ??????? ? ?????????????? ?????????? ???????? ??????. Peterson A?P/?A (???)  
???????????? (???????) ???????? ????????? ???????????? ?????? ???????????? (???????) ???????? ????????? ???????????? ??????
?????? ????????? ????, ??? ??????????? ?????? ????????? Einc 3(1 A/WCSA)/DC (???)  
7
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8
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9
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10
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  • 30 ?????? 20-40 ???, 29,56,5 ???, ? ?? 1
    ??????? (???/???144,515,4/85,48,8 ?? ??.??.),
    ? ?????????????????? ??????????? ?? 1 ????
    ?? 20 ???, ? ??????? 6,14,9 ???.

11
????????????? ??????? ??????????? ????????? ???
?????? 20-40 ??? ? ?? 1 ??.(??????????? ?????? -
??????? ??????) ? ???????? ?????? 30-39 ???
(Chinese Journal of Ultrasonography,
2008,17(7)571-575
?????????? ß Ep kPa AC mm2/kPa PWV m/s
?????? ??? 6,3 2,8 6,8 2,2 ns 95,938 85,730 p0,07 1,00,4 1,00,3 ns 5,83,8 5,93,9 ns
????? ??? 6,52,7 6,51,8 ns 97,033 81,524 p0,0008 0,970,2 1,00,4 ns 5,83,4 5,52,3 ns
12
??????????? ??????????? ????????? ????????? ???
?????? 20-40 ??? ? ?? 1 ??.
ß Ep AC ???-???? ??? ??? ???
ß 1,0 r0,94 r-0,79 r0,65 r0,21 ns r0,38 r0,4
Ep r0,94 1,0 r-0,78 r0,59 r0,51 r0,64 r0,42
AC r-0,79 r-0,78 1,0 r -0,62 r - 0,38 r -0,44 r - 0,4
13
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  • 42 ???????? ? ??? ? ?? ? ???????? ?? 40 ?? 75
    ??? , ?? ??? 20 ??????? ? ?? 2 ???? ? 22 ???????
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    ??????????? ?? ???????? ? ?????? ??.

14
??????????? ???????????? ????????? ? ??????? ???
? ?? ? ?????????? ? ??? ????????? ???????????
??????
??? ?/? ?/? ß ??? Ep ??? kPa ?? ??? mm2/kPa ß ?? Ep ?? kPa ?? ?? mm2/kPa ß ?? Ep ?? kPa ?? ?? mm2/kPa
????? 10,9 2,4 10,52,0 149,436,1 0,740,3 13,35,1 187,674,4 0,240,1 20,05,7 283,386,5 0,050,03
????? ?? 11,72,1 13,54,5 190,169,8 0,640,2 15,78,1 219,1135 0,250,2 24,711,6 357,2188 0,080,1
ns ns ns ns ns ns
ns
?lt0,05 ?lt0,05 ?lt0,05

15
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ESH 2007 ? ??????????? ? ??????? ????????????
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2010, ESH 2007
16
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17
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Determinants of pulse wave velocity in healthy
people and in the presence of cardiovascular risk
actors establishing normal and reference
values European Heart Journal (2010) 31,
23382350
18
1878 (????)
  • ?2 k E (h/R)/?
  • ?????? 20 ????
  • Frank
  • Ludwig
  • Wezler
  • Hurtle
  • Muller
  • ?.?.???????
  • H.?.????????

19
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20
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??? ?? ?? ??????? ??????????? ECG (?? 12
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4 ???????, ECG ?????????, ????????
??, ???, ????????? ???????, ???
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21
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NEW questions What is the best index of the
stiffness cfPWV, aortic PWV, traditional CAVI,
kCAVI, cfCAVI, aortic CAVI (AoVI) , .. ?
Aortic CAVI (AoVI)?
CAVI kCAVI AoVI cfCAVI
caPWV ckneePWV cfemoralPWV (aortic PWV) cfPWV
Cut-off value for cfCAVI IF Cut-off value for
cfPWV10 m/c cfCAVI - 1.9PWV -6.5 19-6.5 13.5
22
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19 ????? 2013 ??????? ?????? 4500 ???????
??????
VaSera
VS-1500 n
Cardiology Research Center, Moscow, Russian
Federation
  • Ivanovo St. Petersburg Vladikavkaz Tomsk
    Tyumen
  • 2000 2000 2000
    2000 2000 participants

23
Correction of 24-h profile of aortic elasticity -
RWTT(Group-Mean 24-h Profile)
24
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    ???????????.

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25
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  • 65 ?????? ??????????????? ????????? ? ?? (1-2
    ??.) ?????? ?????????? ?????? ? ?????
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    ????????, ?. ????????
  • 77 ?????? ??????????????? ????????? ? ?? ??????
    ??????????

26
?????? HLS (N142) ?????? ??????????
In normal coronary arteries, subendocardial
ischemia occurs when SEVR falls below 50 ???
27
  • 24 HOUR PROFILE OF CENTRAL AORTIC PRESSURE, PULSE
    WAVE TRANSIT TIME AND INTENSITY OF REFLECTED
    WAVES IN PATIENTS WITH HYPERALDOSTERONISM
  • Russian Cardiology Scientific Research and
    Production Centre Moscow
  • Petrozavodsk State University Petrozavodsk
    RUSSIA
  • Design and Methods 49 patients (33 men and 16
    women, 43.416.3 years) with AH (24-h BP 147
    15/89 13 mm Hg)
  • and primary or secondary hyperaldosteronism -
    plasma aldosterone concentration (PAC) 152434
    ng/ml/h (Grope Aldo)
  • and 107 practically healthy volunteers (79 men
    and 28 women, 44.46.1 years, 24-h BP 117 5/73
    4 mm Hg)-Grope N.

28
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29
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30
  • ??????? ?? ???????? !!!

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