Bacterial Catabolism

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Bacterial Catabolism

• Introduction
• Glycolysis

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Bacterial Catabolism

• Introduction
• Catabolic activities include the break down of
  glucose to release energy in form of ATP
• Reactions include three pathways
• Glycolysis
• Krebs Cycle
• Oxidative Phosphorylation (Electron Transport)
• Alternative pathways

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Bacterial Catabolism

• Glycolysis - Includes
• Activation
• Oxidation
• ATP Synthesis
• NADH2 Production

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Bacterial Catabolism

• Glycolysis
• splitting of sugar
• Glucose to pyruvate
• Substrate phosphorylation
• 10 reactions / two phases
• Activation
• Energy Production
• Evolution - probably oldest

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Bacterial Catabolism
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Bacterial Catabolism
Activation of glucose by ATP
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Bacterial Catabolism
Activate with second ATP
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Bacterial Catabolism
Split sugar into 2 x 3C molecules
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Bacterial Catabolism
Oxidation and phosphate addition
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Bacterial Catabolism
ATP made at substrate level from 1,3-PGA
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Bacterial Catabolism
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Bacterial Catabolism
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Bacterial Catabolism
Second ATP made from PEP
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Bacterial Catabolism

• Summary of glycolysis
• 1 Glucose to 2 pyruvate
• 2 NADH2 produced
• 2 ATP consumed
• 2 ATP for each 3C molecule produced
• Net yield of 2 ATP

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Bacterial Catabolism

• Anaerobic Fermentation
• NADH2 must be recycled for glycolysis to continue
  to produce ATP
• Pyruvate to lactate
• Pyruvate to ethanol CO2
• Pyruvate to propionate

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Bacterial Catabolism
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Bacterial Catabolism