DNA Damage

1
Gene
Function
Role
DNA Damage
FANCG Double Strand Break Repair Homologous
Recombination PMS1 MLH1 Binding Mismatch Repair
Metabolism
GAD1 Glutamic acid carboyxlase Glutamate
Metabolism GBE1 Glycosidic Bond
formation Glycogen synthesis ALDH6A1 Aldehyde
Dehydrogenase Carbohydrate Metabolism AGPAT1 LPA
acetyltrasferase Phosphatidic Acid
Metabolism ALDH1A3 Aldehyde Dehydrogenase Carbohy
drate Metabolism HEXA Hexoamidase Ganglioside
Metabolism SOAT1 Acetyl Transferase Cholesterol
Metabolism FMO4 TMA Oxidase Amino Acid
Metabolism NDUFB5 Oxidoreductase Electron
Transport NDUFB7 Oxidoreductase Electron
Transport COX5A Cytochrome c oxidase Electron
Transport SDHA Succinate dehydrogenase Electron
Transport PKLR Pyruvate kinase Glycolysis
Apoptosis
CASP6 Caspase Pro-Apoptotic PEA15 DED
Containing Apoptosis CASP3 Caspase Pro-Apoptot
ic DAP1 IFG Signalling Pro-apoptotic TRADD TNF
Signalling Pro-Apoptotic TNFRSF10D TRAIL Decoy
Receptor Anti-Apoptotic
Cell Signalling
EPHB1 Tyrosine Kinase Signalling ARHGAP1 Rho
GAP Signalling MAPKAPK3 Mitogen
Signalling MAPK Pathway FGR Tyrosine
Kinase Cell Migration MAPK10 Mitogen
Signalling MAPK Pathway RAF1 MAP3K MAPK
Pathway FGF2 FGF signalling Signalling FGFR4 FGF
Signalling Signalling IGF2 Mitogen
Signalling Signalling PPARG Transcriptional
Control Signalling RAC1 GTPase Ras Signalling
Transport
SLC2A5 Glucose/Fructose Transport Solute
Carrier AP1G1 Clathrin Vesicles Ligand-Receptor
Transport KCNMB1 Potasium Channel Ion
Channel SLC16A2 Organic Solute Carrier Solute
Carrier ATP5C1 Proton Channel ATP
Synthesis SLC19A1 Folate Transport Solute
Carrier SEC61B ER Channel Protein
Translocation ABCG1 ABC transporter Cholesterol/
phospholipid transport SLC22A1 Organic Cation
Transport Solute Carrier SLC16A4 Monocarboxylic
acid transport Solute Carrier ATP6V0B V-Type
ATPase pH Regulation
Table S2 mRNAs Down-regulated during TRAIL
induced apoptosis