Recombinant%20DNA

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?????

• ?????????
• 2003/05/06

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?????20???????
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(No Transcript)
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???

• ???
• ??(NH2)
• COOH
• ?(H)
• ??(side chain, R)

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?????

• ???????L-????????,?????

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• ?????(Proline)???,??19???????????

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????(Primary Structure)

• ???????????,??peptide bonds,???????

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(No Transcript)
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???(disulfide bond)

• ??????,??????polypeptide chain?????

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Conformation of Polypeptide Chain
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(No Transcript)
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Phi ? Psi ????
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????(Secondary Structure)

• Alpha helix

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• Beta sheet

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(No Transcript)
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• Beta turn

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• Loop

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????(tertiary structure)

• ????????

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????(quaternary structure)

• ?????????????????
• ???????

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???????????

• ???????

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??????????????

• ?????????,???
• ????????????
• Knowledge-based method
• ?????????,???????????????????,????????????????????
  ???
• ?????

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??????

• ???????20???????,????????????????,?????????????

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??????

• Edman degradation

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(No Transcript)
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????DNA

• Genetic code

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• Genetic code ????