Title: MESIAL TEMPORAL SCLEROSIS
1MESIAL TEMPORAL SCLEROSIS
- REVERSED SYMPTOMS
- WITH HOMOEOPATHY
- Dr. Aparna Singh
2LEFT MTS where the arrow points at the lesion
- ATROPHY AND GLIOSIS OF THE NEURONAL CELLS
317/07/2014
- WAS PUT ON ANTI-EPILEPTIC DRUGS, EVEN WHEN THERE
WERE NO SEIZURES- Max Hosp Neurophysician
4NEURONAL LOSS
- The condition called mesial temporal sclerosis is
closely related to temporal lobe epilepsy, a type
of partial (focal) epilepsy in which the seizure
initiation point can be identified within the
temporal lobe of the brain. Mesial temporal
sclerosis is the loss of neurons and scarring of
the deepest portion of the temporal lobe and is
associated with certain brain injuries.
5Brain damage from traumatic injury, infection, a
brain tumor, a lack of oxygen to the brain, or
uncontrolled seizures is thought to cause the
scar tissue to form, particularly in the
hippocampus, a region of the temporal lobe. The
region begins to atrophy neurons die and scar
tissue forms. This damage is thought to be a
significant cause of temporal lobe epilepsy. In
fact, 70 percent of temporal lobe epilepsy
patients have some degree of mesial temporal
sclerosis. It also appears that the mesial
temporal sclerosis can be worsened by additional
seizures.
6Possible Causes
- Aging
- Although the hippocampal sclerosis is relatively
commonly found among elderly people (10 of
individuals over the age of 85 years),
association between this disease and ageing
remains unknown.
7Vascular risk factors
- There were also observations that hippocampal
sclerosis was associated with vascular risk
factors. Hippocampal sclerosis cases were more
likely than Alzheimer's disease to have had a
history of stroke or hypertension, evidence of
small vessel disease but less likely to have had
diabetes mellitus
8Socioeconomic status
- Socioeconomic correlates of health have been well
established in the study of heart disease, lung
cancer, and diabetes. Many of the explanations
for the increased incidence of these conditions
in people with lower socioeconomic status (SES)
suggest they are the result of poor diet, low
levels of exercise, dangerous jobs (exposure to
toxins etc.) and increased levels of smoking and
alcohol intake.
9Symptoms
- Mesial temporal sclerosis usually results in
partial (focal) epilepsy. This seizure disorder
can cause a variety of symptoms such as strange
sensations, changes in behavior or emotions,
muscle spasms, or convulsions, memory loss. The
seizures usually are localized in the brain, but
they may spread to become generalized seizures,
which involve the entire brain and may cause a
sudden loss of awareness or consciousness.
10Symptoms
- Generally, hippocampal sclerosis comes with
epilepsy. It is clarified the nature of insults
that most likely cause hippocampal sclerosis and
initiate the epileptogenic process. Apart from
the chronic nature of epilepsy, hippocampal
sclerosis was shown to have an important role in
internal cardiac autonomic dysfunction. Patients
with left hippocampal sclerosis had more severe
parasympathetic dysfunction as compared with
those with right hippocampal sclerosis. In young
individuals, it is commonly recognized as Mesial
temporal sclerosis with Temporal Lobe
Epilepsy(TLE). On the other hand, it is an often
unrecognized cause of cognitive decline,
typically presenting with severe memory loss.
11Diagnosis
- The changes associated with mesial temporal
sclerosis are usually identifiable on a magnetic
resonance imaging (MRI) scan.
12Conventional Treatment
- ANTI EPILEPTIC DRUGS
- SURGERY-The assessment of the extent of mesial
temporal sclerosis is important because it can be
a good indicator of the outcome for patients
undergoing temporal lobectomy to control
seizures. For this procedure, the part of the
brain containing the point at which the seizures
start is removed. The best outcomes for the
surgery are in patients with mesial temporal
sclerosis on only one side of the brain. Also,
the best outcomes are achieved with complete
removal of the sclerotic medial temporal
structures. This is the single most common
surgery for patients with medically refractory
epilepsy, has a high rate of eliminating seizures
and is associated with a low incidence of
significant new neurological impairments.
13NOW THE CASE IN PARTICULAR
- A 38 yr old male , overweight , had been seeing
me for the past 10 years off and on for his
health issues, mainly ureteric calculi, and pain
renal region, at times left and other times
right. Had been excreting calculi till 1 yr ago.
He has been now in the habit of chewing gutka,
paan masala for the past 6-8 yrs and also takes
alcohol daily, for the past 3-4 years.Eats rich
food and is a non vegetarian, no exercise, also
has a fatty liver.
14ONSET
- On 13th July 2014, Sunday, he took a tab in the
morn-allop. To check the loose stools which he
had in the morning, the same evening his
daughters heavy board fell on his toe and he was
in extreme pain and rushed to some local allop
physician who prescribed analgesics. On 15th July
noon as he was riding his bike, he experienced
some abnormal sensation of fluttering, in the
left side of chest and immediately stopped his
bike and stood. He went on having the sensation
for about 2-5 minutes and then subsided , only to
re occur every 20 min to 30 minutes, he rushed
the same night to synergy hospital and was
admitted for observation for the night for any
cardiac cause. Next day , was discharged and told
that ECG is normal and it is not related to
cardiac cause. Aft paying the bill of 15 K he
came back.
15Case (contd.)
- On 17th July 2014, he noticed that he was also
having a slur in his speech , while this episode
of feeling cold, and almost shuddering with
coldness of left side of the body only , a wave
like sensation originating from chest and moving
both up and down on left limbs and towards face
with piloerection of hair of arm and lacrimation
from left eye. So I went to see a neuro in Max.
He advised MRI- in which a neurological disorder
was confirmed-LEFT MTS.
16NOTES BY MAX NEURO
- Dr Rohtash sharma was the neurophysician, he is
well known in Doon now ?
17PRESCRIPTION BY MAX NEURO
- ANTI EPILEPTICS DRUGS HAVE BEEN PRESCRIBED
18IN HIS OWN WORDS
- 22nd July 2014
- 6 months ago also I had some complaints, of
ghabrahat etc, which I neglected and it got
better on its own. - NOW I HAVE THIS LEFT SIDED COMPLAINT
- SHIVERING FEELING WITH GHABRAHAT FROM CHEST
TRAVELS TO UPPER LIMB AND LOWER LIMB - bolne mei ladkhadahat , bhi hoti hai saath saath
, - pehle cold lagta hai , shivering hoti hai
- FEAR HOTA HAI , DARR LAGTA HAI, ghabrahat I feel
in chest region - WITHDRAWAL OF ALCOHOL AND TABACCO.. Aft that day
have stopped taking alcohol and tobacco
19PEAK OF SUMMER AND NO FAN/A.C
- Since it is peak of summers, I want to have the
right side of body under A.C , and left side
covered by blanket, these sensations are coming
every 20 min, under blanket and covers, little
longer period of say 30 min. I am not even able
to use fan because I feel cold on my left side
and the whole episode reappears more frequently
if I use fan.
20My family and I are in great distress, since I
have been told by neuro that I am not supposed to
drive, since I may black out and fall from a
scooter, my car may meet an accident under Anti
epileptics.Since I am taking these drugs, now
even if a dog barks, I get startled, I dont want
to hear the sound of t.v. I feel sleepy and
misearble aft these drugs.
21GELSEMIUM IS THE PERFECT MATCH
- Gelsemium 200 was given by mouth and aft this one
dose , he said the next episode came aft 40
minutes and the intensity of symptoms was less- - he felt less cold
- the wave started from chest but didnt go into
limb, only ascended upwards, piloerection was
there but less in intensity - Lacrimation lasted for less time and was also
less - Slur of speech also less,
- Ghabrahat was there and episode went off earlier
than prev episodes.
22BRAIN AFFECTIONS OF
- Bry, Nux vom, Gels are the 1st 3 rems
23J.H CLARKE- Amaurosis. Anterior crural neuralgia.
Aphonia. Astigmatism. Bilious fever. Brain,
affections of. Cerebrospinal meningitis.
Choroiditis. Colds. Constipation. Convulsions.
Deafness. Dengue fever. Diarrhoea. Diphtheria.
Dupuytrens contraction. Dysentery. Dysmenia.
Emotions, effects of. Epilepsy. Eyes, affection
of. Fever. Fright. Gonorrhea. Hay-fever.
Headache. Heat, effects of. Heart, diseases of.
Hydro-salpingitis. Hysteria. Influenza.
Intermittent fever. Jaundice. Labour. Liver,
affection of. Locomotor ataxia. Measles.
Meningitis. Menstruation, painful, suppressed.
Metrorrhagia. Myalgia. Neuralgia. Nystagmus.
OEsophagus, stricture of. Paralysis. Paralysis
agitans. Paraplegia. Pregnancy, albuminuria of.
Ptosis. Puerperal convulsions. Remittent fever.
Retina, detachment of. Rheumatism. Sexual excess,
effects of. Sleep, disordered. Spasms.
Sun-headache. Sunstroke. Teething.
Tic-douloureux. Tobacco, effects of. Tongue,
affections of. Toothache. Tremors. Uterus,
affections of. Vertigo. Voice, loss of.
Writers cramp.
24 Neurotic symptoms in cigar-makers, impotence,
palpitation. Aggravation. Damp weather before
a thunderstorm mental emotion or excitement bad
news tobacco smoking when thinking of his
ailments when spoken to of his loss.
2524th July shifted to LM
- On 24th July he reported relief, but said that
the wave is still coming, albeit in a lesser
intensity. - Due to persistence of symptoms he was shifted to
LM potencies of GELSEMIUM LM2 bd .
26STOPPED AFT 3 DAYS, on 26th July 2014
- Aft 3 days of Gelsemium LM2 , given twice a day-
I feel much better - The wave sensation is almost gone
- Dont feel cold, no piloerection on arms and legs
- No slur, no lacrimation
- But on 4th day I felt symptoms increasing again
- STOP GELS LM2 ONLY ON SAC LAC AFT THAT.
276th NOV 2014
- Till 6th Nov 2014, he was on sac lac and then
started to c/o - Left sided headache always worse aft sleeping
- Even if I sleep in daytime, I get this headache
- Morn when I wake up I get this headache of dull
aching nature, feel sleepy and groggy, with a
feeling of palpitation.An hour aft I wake up it
gets better, I have stopped sleeping in daytime,
even though I want to.
28LACHESIS LM2
- Based on left sidedness of headache,
- And
- Worse AFTER SLEEP , either day or night.
- LACH LM2 was given bd
29LATER MRI
- In Jan 2015 MRI was done in Delhi, which revealed
same findings of atrophy and left MTS. Another
MRI was done in Jan 2015 itself, to see the
vascularity, blood flow to the brain, which was
absolutely normal, no obstruction of any vascular
channel.
30JOINED JOB IN JAN 2015
- He has again joined back , has got a better raise
and a better job. - He is not experiencing any of the previous
symptoms .
31WHAT IS TO BE LEARNT HERE
- A SIMPLE MEDICINE CAN CURE/INITIATE CURE EVEN OF
A COMPLICATED DISORDER. - MIASM CONSIDERATION IS NOT NECESSARY, WHEN THE
TOTALITY IS CHARACTERISTIC AND SPEAKS FOR THE
REMEDY. - DELETE FROM THE MIND DISEASE REMEDY RELATIONS-
like for viral/seasonall flus, gels ars acon etc,
for joint pains, rhus tox, .WHO KNEW THAT
REVERSAL OF NEURONAL DAMAGE MANIFESTATIONS CAN BE
INITIATED BY YELLOW JASMINE. - EVEN A HOMOEOPATH CAN BUNGLE CASE IF TOTALITY IS
NOT CONSIDERED.( If Miasm is considered in lieu
of totality) - ATROPHY/SCAR IN BRAIN REMAINS-SYMPTOMS VANISH.