Aarkstore.com Research Report on Chinese Chemosynthetic Polypeptide Drug Industry, 2012

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Aarkstore.com Research Report on Chinese
Chemosynthetic Polypeptide Drug Industry, 2012

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  Aarkstore.com Research Report on Chinese
  Chemosynthetic Polypeptide Drug Industry, 2012
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   Chemosynthetic polypeptide drugs are drugs
combining the certain amino acids in chemical
methods, which are characterized by favorable
curable effects, few side-effects, high
specificities and other advantages.  In the
pharmaceutical industry, chemosynthetic
polypeptides are the focus of attentions. On one
hand, the indications of polypeptide drugs are in
wide range and the curative effects are obvious,
mainly for the application of tumor, metabolism,
cardiovascular diseases, infectious diseases,
etc. On the other hand, the development-success
ratio of polypeptide drugs is high compared to
that of traditional drugs and the approval ratio
is also obviously higher than that of
micromolecule chemical drugs. According to
historical data, the approval ratio of
polypeptide drugs in clinical research is 23 to
26 . As the rapid development of biochemical
technologies and generic engineering field,
polypeptide drugs are likely to replace the
existing medicines.  By the end of 2011, there
were 68 polypeptide drugs approved to the market
(at least to sell in one country)globally, among
which there were 51 treatment drugs mainly used
in 14 cure fields, i.e., tumors,
immunoregulation, cardiovascular diseases,
metabolism, etc. In 2011, the total sales was
about USD 20.8 billion. At present, there are
over 140 polypeptide drugs globally amidst the
clinical trial and also 500 to 600 drugs are at
the stage of research before clinical work. In
the perspective of history, there were 1.2 new
polypeptide drug candidates entering clinical
research period annually in the 70s of 20th
century. The number of new polypeptide drug
candidates was separately 4.6 in the 80s and 9.7
in the 90s. During 2000 and 2008, it was 16.8,
with a steady increasing trend.
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