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Clinopathalogical Conference

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General appearance:A stunted, apathetic girl with protuberant abdomen and ... Intravenous pyelogram:Bilateral enlarged kidneys but no other abnormalities. ... – PowerPoint PPT presentation

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Title: Clinopathalogical Conference


1
Clinopathalogical Conference
  • 2004-05

2
Chief Complaints
  • A 6 ½-year-old girl was admitted to hospital
    because of failure to thrive.

3
Physical Examinations
  • General appearanceA stunted, apathetic girl with
    protuberant abdomen and slender extremities.
  • BW17 Kg (10th percentile) BH96.2 cm (lt3rd
    percentile).
  • Mild generalized muscle hypotonia and enlarged
    abdomen.

4
Laboratory studies
  • Serum uric acid0.55 mmol/l (0.13-0.39)
  • Serum aspartate aminotransferase0.71 µmol.s-1/l
    ()
  • Alkaline phosphatase602 IU/l (145-420)
  • Triglycerides0.6 g/dl (0.35-1.14)
  • Blood sugar1.7 mmol/l (3.3-5.5)
  • Blood lactate8.9 mmol/l (0.8-1.5)

5
Laboratory Studies
  • ABGpH7.32, HCO3-9 mmol/l
  • Repeated Urianalysesno proteinuria or
    abnormality in sediment.
  • Urine cultureNo growth.

6
Other studies
  • Intravenous pyelogramBilateral enlarged kidneys
    but no other abnormalities.
  • Bone radiographsNo rickets or hyperparathyroidism
    .

7
Hospital Course
  • She was treated with sodium bicarbonate for
    metabolic acidosis.
  • Despite increasing the doses or oral sodium
    bicarbonate to 8 mmol/Kg/day, metabolic acidosis
    persisted.

8
Problems List
  • Major Problems
  • Failure to thrive
  • Metabolic acidosis
  • Minor Problems
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