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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - Only need to genotype once. ... Ask one question at a time, or Ask many questions at once? Time. Expense. ... close breakpoints occur in different generations. ...
Only need to genotype once. ... Ask one question at a time, or Ask many questions at once? Time. Expense. ... close breakpoints occur in different generations. ...
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INBRE RESEARCH PROGRAM PowerPoint PPT Presentation
INBRE RESEARCH PROGRAM - Dark blue is endocardium and cushion mesenchyme; Light blue is ECM; Red is myocardial tissue ... LEADERS: ROBERT PRICE (USC) AND JAY JEROME (VANDERBILT) ...
Dark blue is endocardium and cushion mesenchyme; Light blue is ECM; Red is myocardial tissue ... LEADERS: ROBERT PRICE (USC) AND JAY JEROME (VANDERBILT) ...
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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - Reduce individual variation by phenotyping multiple individuals from each strain. ... Characterize the breakpoint process along a chromosome in 8-way RILs. ...
Reduce individual variation by phenotyping multiple individuals from each strain. ... Characterize the breakpoint process along a chromosome in 8-way RILs. ...
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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - Each strain is an eternal resource. Only need to genotype once. Reduce individual variation by phenotyping multiple individuals from each strain. ...
Each strain is an eternal resource. Only need to genotype once. Reduce individual variation by phenotyping multiple individuals from each strain. ...
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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - Title: Understanding human disease via randomized mice Author: Karl Broman Last modified by: Karl W Broman Created Date: 3/2/2005 7:03:11 PM Document presentation format
Title: Understanding human disease via randomized mice Author: Karl Broman Last modified by: Karl W Broman Created Date: 3/2/2005 7:03:11 PM Document presentation format
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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - Small and cheap. Inbred lines. Simpler genetic architecture. Controlled ... The trick that allowed us to get the coincidence for 2-way RILs doesn't work for ...
Small and cheap. Inbred lines. Simpler genetic architecture. Controlled ... The trick that allowed us to get the coincidence for 2-way RILs doesn't work for ...
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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - Study the clustering of the breakpoints, as a function of crossover interference in meiosis. ... Strong positive crossover interference. Inbreed to complete fixation ...
Study the clustering of the breakpoints, as a function of crossover interference in meiosis. ... Strong positive crossover interference. Inbreed to complete fixation ...
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The genomes of recombinant inbred lines PowerPoint PPT Presentation
The genomes of recombinant inbred lines - First generation: Wi = Xi = A, Yi = Zi = B. Then Pr(AA fixed) = 2(q1 q2) Pr(AB fixed) = 4 q3 ... Markov property. 39. Markov property. 40. Markov property. 41 ...
First generation: Wi = Xi = A, Yi = Zi = B. Then Pr(AA fixed) = 2(q1 q2) Pr(AB fixed) = 4 q3 ... Markov property. 39. Markov property. 40. Markov property. 41 ...
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North Dakota INBRE External Advisory Committee Meeting PowerPoint PPT Presentation
North Dakota INBRE External Advisory Committee Meeting - Sitting Bull College. Turtle Mountain Community College. Tribal ... Sitting Bull College. N = 106 ... Sitting Bull College. Macro-invertebrate analysis ...
Sitting Bull College. Turtle Mountain Community College. Tribal ... Sitting Bull College. N = 106 ... Sitting Bull College. Macro-invertebrate analysis ...
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Inbred strains of mice are: PowerPoint PPT Presentation
Inbred strains of mice are: - Are derived from 20 or more brother-sister matings ... distance (in meters) between successive foot prints in the snow is an example of: ...
Are derived from 20 or more brother-sister matings ... distance (in meters) between successive foot prints in the snow is an example of: ...
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Winthrop University Nov '05 SC EAS INBRE Presentation PowerPoint PPT Presentation
Winthrop University Nov '05 SC EAS INBRE Presentation - Winthrop University Nov '05 SC EAS INBRE Presentation
Winthrop University Nov '05 SC EAS INBRE Presentation
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Inbred Line Development and Hybrid Evaluation in GEM Breeding Crosses PowerPoint PPT Presentation
Inbred Line Development and Hybrid Evaluation in GEM Breeding Crosses - Inbred Line Development and Hybrid Evaluation in GEM Breeding Crosses ... and biotic factors, and adaptation to the Mid-Atlantic and Corn Belt regions ...
Inbred Line Development and Hybrid Evaluation in GEM Breeding Crosses ... and biotic factors, and adaptation to the Mid-Atlantic and Corn Belt regions ...
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Dickinson State University INBRE Program April 2006 PowerPoint PPT Presentation
Dickinson State University INBRE Program April 2006 - Our hypothesis is that lycopene's anticarcinogenic properties ... HS-68, foreskin fibroblast cells. A549, lung carcinoma cells. HS-578T, breast carcinoma cells ...
Our hypothesis is that lycopene's anticarcinogenic properties ... HS-68, foreskin fibroblast cells. A549, lung carcinoma cells. HS-578T, breast carcinoma cells ...
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Fine mapping QTLs using Recombinant-Inbred HS and In-Vitro HS PowerPoint PPT Presentation
Fine mapping QTLs using Recombinant-Inbred HS and In-Vitro HS - Detecting a significant locus ... Mapping accuracy for significant loci. Mean mapping error = average distance between true QTL and the predicted locus ...
Detecting a significant locus ... Mapping accuracy for significant loci. Mean mapping error = average distance between true QTL and the predicted locus ...
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INBRE North Dakota IDeA Networks for Biomedical Research Excellence Building biomedical research cap PowerPoint PPT Presentation
INBRE North Dakota IDeA Networks for Biomedical Research Excellence Building biomedical research cap - North Dakota INBRE Program Coordinator, Dr. Donald Schwert, NDSU, donald.schwert ... Director- Dr. Phil McClean ... Educational Specialist: Dr. Jerzy (George) ...
North Dakota INBRE Program Coordinator, Dr. Donald Schwert, NDSU, donald.schwert ... Director- Dr. Phil McClean ... Educational Specialist: Dr. Jerzy (George) ...
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A sequencebased variation map of 8'27 million SNPs in inbred mouse strains PowerPoint PPT Presentation
A sequencebased variation map of 8'27 million SNPs in inbred mouse strains - A sequence-based variation map of 8.27 million SNPs in inbred mouse strains ... Segmental phylogenetic relationships of inbred mouse strains revealed by fine ...
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains ... Segmental phylogenetic relationships of inbred mouse strains revealed by fine ...
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INBRE Bioinformatics in Research and Education at IDeA Institutions PowerPoint PPT Presentation
INBRE Bioinformatics in Research and Education at IDeA Institutions - ... and students research support, serve as 'pipeline' to health research careers. ... NIH National Institute of General Medical Sciences ...
... and students research support, serve as 'pipeline' to health research careers. ... NIH National Institute of General Medical Sciences ...
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Winthrop University Nov '05 SC EAS INBRE Presentation PowerPoint PPT Presentation
Winthrop University Nov '05 SC EAS INBRE Presentation - for South Carolina State Teaching Universities. Teaching University FY03-04 ... Director, Biology Division, Orthopaedic Research Laboratory,Carolinas Medical ...
for South Carolina State Teaching Universities. Teaching University FY03-04 ... Director, Biology Division, Orthopaedic Research Laboratory,Carolinas Medical ...
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Annual Progress Reports and Program Evaluation INBRE Central Regional Meeting May 56, 2005 PowerPoint PPT Presentation
Annual Progress Reports and Program Evaluation INBRE Central Regional Meeting May 56, 2005 - apologies to Elizabeth Barrett Browning. Publications. Publications. Publications. Publications ... Presentations at local, regional, national and ...
apologies to Elizabeth Barrett Browning. Publications. Publications. Publications. Publications ... Presentations at local, regional, national and ...
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South Carolina IDeA Network of Biomedical Research Excellence SC INBRE CLEMSON UNIVERSITY: Cardiovas PowerPoint PPT Presentation
South Carolina IDeA Network of Biomedical Research Excellence SC INBRE CLEMSON UNIVERSITY: Cardiovas - South Carolina IDeA Network of Biomedical Research Excellence SC INBRE CLEMSON UNIVERSITY: Cardiovas
South Carolina IDeA Network of Biomedical Research Excellence SC INBRE CLEMSON UNIVERSITY: Cardiovas
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Types of Releases and Seed Certification PowerPoint PPT Presentation
Types of Releases and Seed Certification - Commercial [Cultivars or Inbred Lines] Cultivar: an economic subdivision of a species ... inbred x inbred inbred x OP etc. Seed Certification Definitions ...
Commercial [Cultivars or Inbred Lines] Cultivar: an economic subdivision of a species ... inbred x inbred inbred x OP etc. Seed Certification Definitions ...
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Rat Model Market Overview: Analysis and Insights 2024-2033 PowerPoint PPT Presentation
Rat Model Market Overview: Analysis and Insights 2024-2033 - Global rat model market size is expected to reach $2.34 Bn by 2028 at a rate of 8.5%, segmented as by type, knockout, outbred, inbred, hybrid, immunodeficient, conditioned
Global rat model market size is expected to reach $2.34 Bn by 2028 at a rate of 8.5%, segmented as by type, knockout, outbred, inbred, hybrid, immunodeficient, conditioned
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Mating Systems PowerPoint PPT Presentation
Mating Systems - Reduction in fitness in inbred individuals. Proper development. Disease resistance ... Non-Inbred vs. Inbred Crested Wood Partridges at the MN Zoo. 8% reduction ...
Reduction in fitness in inbred individuals. Proper development. Disease resistance ... Non-Inbred vs. Inbred Crested Wood Partridges at the MN Zoo. 8% reduction ...
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Gene mapping in model organisms PowerPoint PPT Presentation
Gene mapping in model organisms - Inbred mice. 4. Advantages of the mouse. Small and cheap. Inbred lines. Large, controlled crosses ... Must genotype each mouse. ...
Inbred mice. 4. Advantages of the mouse. Small and cheap. Inbred lines. Large, controlled crosses ... Must genotype each mouse. ...
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Plant Genetics PowerPoint PPT Presentation
Plant Genetics - A plant or animal is only as developed as its genetic components. ... Inbred parent A x Inbred Parent B. Single cross AxB. Three Way Cross ...
A plant or animal is only as developed as its genetic components. ... Inbred parent A x Inbred Parent B. Single cross AxB. Three Way Cross ...
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Managed Breeding for Conservation: Sustainability of Ex Situ Populations PowerPoint PPT Presentation
Managed Breeding for Conservation: Sustainability of Ex Situ Populations - Inbreeding is Reversible If an inbred animal is bred with an unrelated animal, the resulting offspring are not inbred Outbreeding Outbreeding Unrelated Animals Non- ...
Inbreeding is Reversible If an inbred animal is bred with an unrelated animal, the resulting offspring are not inbred Outbreeding Outbreeding Unrelated Animals Non- ...
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Race and Racism PowerPoint PPT Presentation
Race and Racism - Race and Racism * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Races as families or inbred lines 16th & 17th C: race used interchangeably with type ...
Race and Racism * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Races as families or inbred lines 16th & 17th C: race used interchangeably with type ...
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Rapid growth of urban areas in low-income countries PowerPoint PPT Presentation
Rapid growth of urban areas in low-income countries - Inbred wolf Brownfield A grit infection Gentrification Bin grand beggar Garden grabbing I ad a nutrition s Deindustrialisation Upload toe nip Depopulation Cow ...
Inbred wolf Brownfield A grit infection Gentrification Bin grand beggar Garden grabbing I ad a nutrition s Deindustrialisation Upload toe nip Depopulation Cow ...
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Acquired Immunity PowerPoint PPT Presentation
Acquired Immunity - Tx between individuals of the same inbred strain will succeed. Tx between inbred strains are rejected. Tx parent to F1 will succeed, but the reverse will fail. ...
Tx between individuals of the same inbred strain will succeed. Tx between inbred strains are rejected. Tx parent to F1 will succeed, but the reverse will fail. ...
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U24 RESOURCE DISCOVERY: eaglei PowerPoint PPT Presentation
U24 RESOURCE DISCOVERY: eaglei - Oregon Health & Science University. CTSA, NPRC. Dartmouth College. COBRE, INBRE ... exponential impact on the scientific community. ...
Oregon Health & Science University. CTSA, NPRC. Dartmouth College. COBRE, INBRE ... exponential impact on the scientific community. ...
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Basic genetics PowerPoint PPT Presentation
Basic genetics - The gray- coated mouse was extensively inbred and therefore was considered to be ... In mice, coat color is controlled by the B gene. ...
The gray- coated mouse was extensively inbred and therefore was considered to be ... In mice, coat color is controlled by the B gene. ...
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Genetics of lab animals PowerPoint PPT Presentation
Genetics of lab animals - Reducing experimental errors due to uncontrolled genetic variation. Refinement ... fish (gynogenesis also) Inbreds - problems. Inbreeding depression (F2-F8) Mutations ...
Reducing experimental errors due to uncontrolled genetic variation. Refinement ... fish (gynogenesis also) Inbreds - problems. Inbreeding depression (F2-F8) Mutations ...
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MHC and PowerPoint PPT Presentation
MHC and - MHC genes are inherited as a set (haplotype) 1 from mother, one from father. Crossing-over can ... Strain Haplotype. MHC and AG Presentation. 14. Inbred mice ...
MHC genes are inherited as a set (haplotype) 1 from mother, one from father. Crossing-over can ... Strain Haplotype. MHC and AG Presentation. 14. Inbred mice ...
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PCR-based Species Identification and Gene Tagging PowerPoint PPT Presentation
PCR-based Species Identification and Gene Tagging - AFLP templates from parental inbreds BTx623 (cg1cg1) and SC748-5 (Cg1Cg1) and IS3620C (mapping parent) were run as controls to aid in the identification of ...
AFLP templates from parental inbreds BTx623 (cg1cg1) and SC748-5 (Cg1Cg1) and IS3620C (mapping parent) were run as controls to aid in the identification of ...
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How to phenotype my mouse at Penn PowerPoint PPT Presentation
How to phenotype my mouse at Penn - genetically engineered, as well as inbred strains of mice. ... 'The laboratory mouse is hailed as holding the experimental key to the human genome' ...
genetically engineered, as well as inbred strains of mice. ... 'The laboratory mouse is hailed as holding the experimental key to the human genome' ...
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Biotechnology PowerPoint PPT Presentation
Biotechnology - ... organisms with specific characteristics generation after generation. recessive traits can surface that are harmful. Pure bred dogs are inbred. Genetic engineering ...
... organisms with specific characteristics generation after generation. recessive traits can surface that are harmful. Pure bred dogs are inbred. Genetic engineering ...
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DNA Methylation PowerPoint PPT Presentation
DNA Methylation - Mice mated a/a dam X Avy/a sire while the dam is on control ... to 100 y of age) and in some inbred rodent strains (18 to 33 mo of age, scales are approximate) ...
Mice mated a/a dam X Avy/a sire while the dam is on control ... to 100 y of age) and in some inbred rodent strains (18 to 33 mo of age, scales are approximate) ...
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Mapping PowerPoint PPT Presentation
Mapping - determining the location of elements within a genome, with respect ... Theta calculation with inbred populations/strains... bn. det det bn. bn det. det. bn ...
determining the location of elements within a genome, with respect ... Theta calculation with inbred populations/strains... bn. det det bn. bn det. det. bn ...
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The evolution of inbreeding depression in a metapopulation PowerPoint PPT Presentation
The evolution of inbreeding depression in a metapopulation - Inbreeding depression---reduction in fitness of inbred individuals ... A case in China: Panda nature reserves. Limitations in Current research. No extinction ...
Inbreeding depression---reduction in fitness of inbred individuals ... A case in China: Panda nature reserves. Limitations in Current research. No extinction ...
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Genomic Conflict and DNA Sequence Variation PowerPoint PPT Presentation
Genomic Conflict and DNA Sequence Variation - Present need: model-based interpretation of observed patterns of genomic variation ... Relative viability of inbred offspring (s ) Full SC. Polymorphism. Full SI ...
Present need: model-based interpretation of observed patterns of genomic variation ... Relative viability of inbred offspring (s ) Full SC. Polymorphism. Full SI ...
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Inbreeding and Longevity in Bernese Mountain Dogs PowerPoint PPT Presentation
Inbreeding and Longevity in Bernese Mountain Dogs - Scientific: The probability that two alleles at a locus are identical by descent. ... If the dam and the sire are related the resulting puppies will be inbred. ...
Scientific: The probability that two alleles at a locus are identical by descent. ... If the dam and the sire are related the resulting puppies will be inbred. ...
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Bull selection based on QTL for specific environments PowerPoint PPT Presentation
Bull selection based on QTL for specific environments - ... impact on competitiveness and the sustainability of the dairy cattle industry. ... of QTL are based on crosses of genetically distinct breeds or inbred lines. ...
... impact on competitiveness and the sustainability of the dairy cattle industry. ... of QTL are based on crosses of genetically distinct breeds or inbred lines. ...
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Inbreeding PowerPoint PPT Presentation
Inbreeding - It is measured as the probability that two alleles at a locus are identical ... In the pygmy hippopotamus, inbred offspring had 55% juvenile mortality, while ...
It is measured as the probability that two alleles at a locus are identical ... In the pygmy hippopotamus, inbred offspring had 55% juvenile mortality, while ...
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Animals models for host-defense and ethics relating to use of animals in research PowerPoint PPT Presentation
Animals models for host-defense and ethics relating to use of animals in research - Animals models for host-defense and ethics relating to use of animals in research Objectives Brief review of animal (inbred mice) use and contributions in immunology ...
Animals models for host-defense and ethics relating to use of animals in research Objectives Brief review of animal (inbred mice) use and contributions in immunology ...
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Mouse Cancer Models: Incorporation into Translational Research and Personalized Medicine PowerPoint PPT Presentation
Mouse Cancer Models: Incorporation into Translational Research and Personalized Medicine - Incorporation into Translational Research and ... How will they be used in cancer research? Cancer genetics ... Normal inbred laboratory mice and ...
Incorporation into Translational Research and ... How will they be used in cancer research? Cancer genetics ... Normal inbred laboratory mice and ...
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Despite overwhelming evidence from laboratory PowerPoint PPT Presentation
Despite overwhelming evidence from laboratory - results in a decline in the mean for reproductive ... Remedy for inbreeding depression is to outcross. the inbred population to another unrelated ...
results in a decline in the mean for reproductive ... Remedy for inbreeding depression is to outcross. the inbred population to another unrelated ...
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Ramos Lab Tour PowerPoint PPT Presentation
Ramos Lab Tour - PEA-15 KO Mice-Inbred Strain. Well cared for in our beautiful new Animal Facility! ... Mouse Facilities-Preparatory (Gamma Irradiator for Bone Marrow ...
PEA-15 KO Mice-Inbred Strain. Well cared for in our beautiful new Animal Facility! ... Mouse Facilities-Preparatory (Gamma Irradiator for Bone Marrow ...
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7th External Program and Management Review of IRRI PowerPoint PPT Presentation
7th External Program and Management Review of IRRI - EPMRs are jointly managed on behalf of the CGIAR by the Science Council and the ... and broadening the genetic variability, of parental inbred lines. ...
EPMRs are jointly managed on behalf of the CGIAR by the Science Council and the ... and broadening the genetic variability, of parental inbred lines. ...
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Making the Intermated B73 X MO17 mapping population PowerPoint PPT Presentation
Making the Intermated B73 X MO17 mapping population - Making the Intermated B73 X MO17 mapping population of recombinant inbred lines (RILs) Mo17 B73 X Single F2 plant was selfed You test your population of plants for ...
Making the Intermated B73 X MO17 mapping population of recombinant inbred lines (RILs) Mo17 B73 X Single F2 plant was selfed You test your population of plants for ...
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Keeshond Club Genetic Counselling Scheme PowerPoint PPT Presentation
Keeshond Club Genetic Counselling Scheme - The idea of a genetic tendency to epilepsy was first ... All the fitters were found to be inbred to either a dog born in 1971, or to his great grandsire. ...
The idea of a genetic tendency to epilepsy was first ... All the fitters were found to be inbred to either a dog born in 1971, or to his great grandsire. ...
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ID C57 AJ Balb 129 PowerPoint PPT Presentation
ID C57 AJ Balb 129 - ... survival times of inbred mouse strains vary substantially after infection. ... Firstly, congenic mice lines carrying defined regions of the C57BL/6 genome on ...
... survival times of inbred mouse strains vary substantially after infection. ... Firstly, congenic mice lines carrying defined regions of the C57BL/6 genome on ...
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Gentica Molecular em Anlises Clnicas PowerPoint PPT Presentation
Gentica Molecular em Anlises Clnicas - Skin from an inbred mouse grafted onto the same strain of mouse ... Immunogenetics of graft rejection. F1 hybrid (one set of alleles from each parent) A x B ...
Skin from an inbred mouse grafted onto the same strain of mouse ... Immunogenetics of graft rejection. F1 hybrid (one set of alleles from each parent) A x B ...
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BLUP for Purelines PowerPoint PPT Presentation
BLUP for Purelines - ... 1 Set 1 4.82 2 Set 2 5.41 u1 Morex -0.33 u2 Robust -0.17 u3 Excel 0.18 u4 Stander 0.36 BLUP estimates For a set of recombinant inbred lines from an F2 cross ...
... 1 Set 1 4.82 2 Set 2 5.41 u1 Morex -0.33 u2 Robust -0.17 u3 Excel 0.18 u4 Stander 0.36 BLUP estimates For a set of recombinant inbred lines from an F2 cross ...
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TOPIC FOUR: INHERITANCE OF A SINGLE GENE PowerPoint PPT Presentation
TOPIC FOUR: INHERITANCE OF A SINGLE GENE - TOPIC FOUR: INHERITANCE OF A SINGLE GENE Why can t we all just get along and, say, call an inbred line in the F6 generation simply an F6 line ?
TOPIC FOUR: INHERITANCE OF A SINGLE GENE Why can t we all just get along and, say, call an inbred line in the F6 generation simply an F6 line ?
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