Cloning

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Cloning
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Learning Objectives

• To understand the process that was used to clone
  Dolly
• To be able to debate the moral and ethical issues
  associated with cloning

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Cloning

• to create a genetically identical copy of an
  organism

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Dolly
The worlds most famous sheep because she was the
first cloned mammal.

• So how was she made?

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3. An egg cell was taken from a Scottish
Blackface ewe
1. A cell was taken from a Finn Dorset ewe
4. The nucleus was removed discarded
2. The nucleus was removed
5. The nucleus from the Finn Dorset cell was then
transferred into the egg cell
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Here is a photo of the nucleus being transferred
into the egg cell taken using a very strong
microscope
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6. The egg cell with its new nucleus was put into
another sheep.
This sheep was now pregnant!
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7. Dolly was born 148 days later
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In her lifetime she gave birth to 6 lambs
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• Dolly lived until she was 6 years old

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When she died she was preserved you can visit
her at Edinburghs Royal Museum
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Bioethics of Cloning

• Why would you clone?
• What are the benefits
• of cloning?
• What are the concerns
• associated with cloning?

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1. Endangered extinct animals could be saved

• 2. It is unnatural

3. It is risky
4. Therapeutic cloning could be used to treat
people with life threatening diseases
6. Cloned meat could guarantee safe reliable meat
for human consumption
5. Nobody knows the effect cloning would have on
humans
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For Against
1) Endangered extinct animals could be saved.
2) It is unnatural. 3) It is risky. 4)
Therapeutic cloning could be used to treat
people with life threatening diseases. 5)
Nobody knows the effect cloning would have on
humans. 6) Cloned meat could guarantee safe
reliable meat for human consumption.
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Who is it ok to clone?
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Traffic lights

• Do I understand the process that was used to
  clone Dolly?
• Can I debate the moral and ethical issues
  associated with cloning?
• Are you red, amber or green?

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Slide show produced by Chloe Williams.
Image Credits Dolly images kindly provided by
The Roslin Institute. Nuclear transfer images
kindly provided by the Roslin Institiute and the
University of Edinburgh courtesy of Dr. Paul De
Sousa and Dr. Bill Ritchie. Bacteria image kindly
provided by Dr. Garry Blakely from the University
of Edinburgh. Frog image kindly provided by Dr.
Alastair Wilson from the University of Edinburgh.
Kindly funded by
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a) The egg cell with its new nucleus was put into
another sheep. This sheep was now pregnant! b)
An egg cell was taken from a Scottish Blackface
ewe. c) The nucleus was removed. d) Dolly was
born 148 days later. e) A cell was taken from a
Finn Dorset ewe. f) The nucleus from the Finn
Dorset cell was then transferred into the egg
cell. g) The nucleus was removed discarded.
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1. A cell was taken from a Finn Dorset ewe
3. An egg cell was taken from a Scottish
Blackface ewe
1
3
2
5
2. The nucleus was removed
4. The nucleus was removed discarded
5. The nucleus from the Finn Dorset cell was
then transferred into the egg cell
6. The egg cell with its new nucleus was put into
another sheep. This sheep was now pregnant!
6
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7. Dolly was born 148 days later