PowerPointPrsentation

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RIP 3.2-2 Testing Project Alkyl Sulphates June -
August 2007 Frank Wangemann / Ralf-Peter Schuster
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RIP 3.2-2 Testing Project Alkyl Sulphates

• Exposure Scenarios
• covered
• Correlation cTGD
• Use Descriptor 3
• and ES in
• ECETOC TRA

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RIP 3.2-2 Testing Project Alkyl Sulphates

• Description by Exposure Scenarios of ECETOC TRA
  preferred against Use Descriptors of cTGD
• Industrial On-site use in ECETOC TRA
• Professional Non-dispersive use
• Professional / Consumer Wide-dispersive use

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RIP 3.2-2 Testing Project Alkyl Sulphates

• Exposure Scenarios
• Set up for workers (acute, repeated) and
  consumers (repeated)
• Workers ES divided into industrial and
  professional uses
• Acute exposure covered by DNEL, RMM (workers
  only)
• Repeated (short / long term) exposure calculated
  by ECETOC TRA (mainly Tier 2)
• Consumer exposure does not require Tier 2
  calculations
• RMM mainly taken into account for workers
  exposure
• No environmental ES as no environmental hazard
  occurs

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1. Title ES 2. Description of activities 3.
Operational Cond. 3.1 Duration/ frequency 3.2
Maximum amount Used n.a. 3.3 Other op. cond. 4.
Physical form 5. Product spec. (concentration in
prep/article) 6. RMM 7. Waste related Measures
n.a. 8a. Prediction of Exposure in CSR only 8b.
Derived control threshold 9. Set of variables
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RIP 3.2-2 Testing Project Alkyl Sulphates

• Extended SDS Human Health Inhalation - Acute
• Acute exposure covered by DNEL, RMM (workers
  only)
• Acute exposure of consumers is not relevant,
  only repeated

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RIP 3.2-2 Testing Project Alkyl Sulphates

• E-SDS Human Health Inhalation Repeated /
  longterm

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RIP 3.2-2 Testing Project Alkyl Sulphates E-SDS
Human Health - Dermal
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RIP 3.2-2 Testing Project Alkyl Sulphates

• cTGD / CSR / ES general remarks
• Use descriptors of ECETOC TRA are recommended as
  linked to real exposure situations drop use
  descriptors of cTGD
• Due to numerous determinants influencing aerosol
  formation (substance specific, technical,
  environment) not covered by ES - the DU has to do
  its own ES (required data are all in e-SDS)
• ES covers the substance commercialised in solid
  state, and its use in aqueous solutions
  spraying of aqueous solutions to yield powder is
  not covered by ES

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RIP 3.2-2 Testing Project Alkyl Sulphates

• cTGD / CSR / ES general remarks
• A summary of all exposure scenarios would lead to
  unrealistic high figures of exposure or
  unmanageable figure of combinations Guidance in
  cTGD needed
• RMM efficiency is part of exposure estimation
  RMM library to be seen as an orientation tool
  only
• Basic conditions of use (duration, concentration
  limits, efficiency of RMM) decisive for actual
  exposure. Complete set as background document
  ECETOC TRA (freely available, free of charge)
• Exposure values lower comprehensibility

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Cognis Proposal for e-SDS

• Structured format of ES with fixed Phrases
• Headings and content of ES as in cTGD
• IT-suitable output from common SDS systems
• Proper translation into required languages
• Comparability for Industrial DU and Formulator
• (e.g. identification of risk determining
  substance holistic view on exposure pathways
  needed IT-suitable input demanded)
• Readability improved - Basic conditions of use
  only (duration, concentration limits, efficiency
  of RMM)
• Transparency and Completeness ECETOC TRA as
  background document (freely available, free of
  charge)