Aerobic Energy Production During Exercise

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Aerobic Energy Production During Exercise

• PED 5230

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Aerobic Metabolism Overview
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Aerobic Glycolysis
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Krebs Cycle
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Beta Oxidation
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Amino Acids
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Krebs Cycle
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Aeobic Fuel Sources
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Krebs Cycle
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Electron Transport Chain
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Electron Transport Chain
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Free Radicals

• Free radical - molecule with an unpaired electron
• Oxygen
• Superoxide O2-)
• Other
• Hydrogen peroxide (H2O2)
• Nitric oxide (NO-)
• Hydroxyl radicals (HO-)

pp 119-120
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Free Radicals

• Con React with DNA, RNA, proteins, lipids, etc.
• Pro May promote adaptive changes

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Summary
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Control of Bioenergetics
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Aerobic Energy at Rest

• Fuel?
• Lactate?

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Aerobic Energy at Rest

• Oxygen
• VO2 3.5 ml/kg/min
• Oxygen supply easily meets oxygen demand
• C6H12O6 6O2 ? 6CO2 6H2O
• C16H32O2 23O2 ? 16CO2 16H2O

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Aerobic Energy at Rest

• Respiratory exchange ratio (RER or R)
• R VCO2 / VO2
• Fat (palmitic acid) C16H32O2
• C16H32O2 23O2 ? 16CO2 16H2O ATP
• R VCO2/VO2 16 CO2 / 23O2 0.70
• Glucose C6H12O6
• C6H12O6 6O2 ? 6CO2 6H2O ATP
• R VCO2/VO2 6 CO2 / 6O2 1.00

It takes more O2 to burn fats so the R value for
fats will be lower.
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Aerobic Energy at Rest

• Carbohydrates and Fats (very little Protein)

Resting
Low Intensity
High Intensity
Max. Intensity
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Light Aerobic Exercise

• Intensity less than 50 of VO2max
• Steady state
• Oxygen supply Oxygen demand
• Low energy demand
• Fuel?

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HORMONES Epinephrine, Cortisol, Growth Hormone
Triglyceride
Fat Mobilization
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Fat Mobilization
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Fat Mobilization
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Light Aerobic Energy

• Fat mobilization
• Inhibited by lactic acid
• Enhanced by caffeine?

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Fat Burning Zone?
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Fat Burning Zone?
A
B

• Would you rather have 10 of person As money or
  90 of person Bs money?

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Fat Burning Zone?
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Light Aerobic Exercise

• Role of carbohydrates?
• CNS and glucose

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Light Aerobic Exercise
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Light Aerobic Exercise

• Removal Production

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Light Aerobic Exercise
The Cori Cycle