BLOOD TESTING STATUS

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BLOOD TESTING STATUS
Rune Andersen Director, Standards Harmonization
ANADO - Bern, 4-5 November 2004
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HISTORY

• 16 years of deliberation
• Medical, legal, ethical, scientific
• Medical tests vs doping tests
• Screening tests vs doping tests
• Some NADOs - UCI FIS IBU IAAF
• Transfusions Lillehammer 94

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FUTURE
Blood Collection is A MUST
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STATUS
Why Blood?
hGH
HBOCs
Blood Transfusions

• More to come
• Insulin
• IGF-1
• ?
• ?

Only detected in blood
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hGH
( fat mass, muscle recovery, anabolic)
The List Under S.5. Peptide Hormones

• Erythropoietin (EPO)
• Growth Hormone (hGH) and Insulin-like Growth
  Factor (IGF-1)
• Chorionic Gonadotrophin (hCG) prohibited in males
  only
• Pituitary and synthetic gonadotrophins (LH)
  prohibited in males only
• Insulin
• Corticotrophins.

In 2005 List S2 (Hormones and Related
Substances)
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HBOCs
(Hemoglobin Substitutes O2 Transport)
The List Under M.1. Enhancement of Oxygen Transfer
Hemoglobin-Based Oxygen Carriers
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BLOOD TRANSFUSION
(increase the number of red blood cells)
The List Under M.1. Enhancement of Oxygen Transfer

• Traditionally called blood doping
• Misuse of
• Autologous your own blood
• Homologous your blood type from another person
• Heterologous another blood type than yours

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hGH

• Who All sports
• When Pre-competition / 4-10 days prior to
  events. During or after intensive
  training periods
• Analyses Athens, London, Sydney (small
  capacity)
• Type of blood component Serum
• Cool/Freeze Freeze (transport cool is OK)
• Price lab equipment 35,000 USD
• Price analysis Not expensive

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HBOCs

• Who Endurance sports
• When Prior to and in competition
• Analyses Athens, Paris (now), requested to all
  labs
• Type of blood component Serum
• Cool/Freeze Freeze (transport cool is OK)
• Price lab equipment Not expensive
• Price analysis Not expensive

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BLOOD TRANSFUSION

• Who Endurance sports
• When Just prior to, in and 30-45 days after
  competition
• Analyses Lausanne (capacity 20-40 samples per
  week)
• Type of blood component Whole blood
• Cool/Freeze Cooled, not to be frozen
• Price lab equipment 100,000 USD
• Price analysis Approximately 280 SFR

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WHAT NEXT?

• Meeting between WADA and experts 8-9 November in
  Lausanne
• Evaluate Athens pre / post
• Recommendation for the future
• Information to WADA ExCo / FB in late November
• ADOs and laboratories informed and involved in
  future actions

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Blood Collection for hGH / HBOCs
Step 1
Step 2
Step 3
Serum
Result from centrifuge
Placed in plastic bag
Red blood cells
Blood sits for 20 minutes (coagulation)
(Collected from Athlete)
Blood centrifuged for 10 minutes
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Step 4
Athlete provided
A
B
Placed in bag
Serum
Collected from athlete
Red blood cells
Purpose of hGH/HBOCs already centrifuged
Purpose of blood transfusion
Step 5
Secured in bottles
Bag
Bag
Bag
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Step 6
A
B
B
A
HGH and HBOCS (can be frozen)
Blood transfusion (not to be frozen)
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Blood Collection for Athens

• hGH (Centrifuged serum) (can be frozen)
• HBOCs (Centrifuged serum) (can be frozen)
• Blood Transfusions (whole blood) (not to be
  frozen)

Collection method _at_ Olympic Games
For Serum (after centrifugation)
Tab
Tab
B
A
B
Athlete provided
Placed in bag
Serum
Red blood cells
A
A
B
B
Purpose of hGH/ HBOCsAlready centrifuged
Purpose of blood transfusion
Secured in bottles
Sent to lab
Whole blood
Serum
A
A
B
B
A
B
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