PARVOVIRIDAE

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PARVOVIRIDAE

• PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS
• Department of Pathology and Infectious Diseases,
  The Royal Veterinary College,
• Royal College Street,
• London NW1 OTU.
• E-mail Web site

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LEARNING OBJECTIVESStudents should be able to

• Relate the pathogenesis of feline infectious
  enteritis virus to its control
• Explain the origins of canine parvovirus type 2
  and its role in canine disease
• Describe the importance and control of porcine
  parvovirus as a reproductive pathogen
• List the species and disease conditions in which
  papilloma viruses are implicated

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FAMILY CHARACTERISTICS
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FELINE PARVOVIRUS

• DISEASE AND PATHOGENESIS

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FELINE PARVOVIRUS

• DIAGNOSIS

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FELINE PARVOVIRUS

• HOST RANGE All felidae mustelidae (mink) and
  some procyonidae (racoons and panda).

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FELINE PARVOVIRUS

• ANTIGENICITY CONTROL

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CANINE PARVOVIRUS TYPE 2
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CANINE PARVOVIRUS TYPE 2

• DISEASE AND PATHOGENESIS Infection via
  oropharyngeal route followed by viraemia.
• Initially, there were two distinct syndromes
  associated with CPV-2 (1) targeted at rapidly
  dividing myocardial cells, (2) at the rapidly
  dividing cells in the crypt epithelium of the
  small intestine.

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CANINE PARVOVIRUS TYPE 2

• DIAGNOSIS

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CANINE PARVOVIRUS TYPE 2

• HOST RANGE Dogs (but CPV-2a 2b can cause
  disease in cats - see below)

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CANINE PARVOVIRUS TYPE 2

• ANTIGENICITY CONTROL

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PORCINE PARVOVIRUS

• DISEASE AND PATHOGENESIS

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PORCINE PARVOVIRUS

• HOST RANGE pigs

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PORCINE PARVOVIRUS

• EPIZOOTIOLOGY

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PORCINE PARVOVIRUS

• ANTIGENICITY CONTROL

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SUMMARY

• Cause serious diseases in cats (enteritis/
  panleucopenia), dogs (myocarditis/ enteritis) and
  pigs (SMEDI).
• Pathogenesis is related to the requirement for
  rapidly dividing cells for virus replication
• Vaccines available for each disease which prevent
  viraemia hence destruction of rapidly dividing
  cells.