Potential . Fate

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Potential gt. Fate 2 cell stage each cell is
totipotent (Nuclei are totipotent Nuclear
Transfer Experiments Pluripotent Cells are
Determined Potential Fate Determined Inductio
n Competence
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What is the Inducer? Are cells Determined? Is
it reversible or irreversible? Are cells
Competent? At all times?
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Spemann and Mangold The Organizer
http//www.devbio.com/article.php?ch10id114
The Inducer of Neural Ectoderm is ______.
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Is all Ectoderm competent at all times? Dorsal
Lip transfer to Early Gastrula Dorsal Lip
transfer to Late Gastrula
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Is Determination Irreversible? Future Neural
Ectoderm from Early Gastrula Future Neural
Ectoderm from Late Gastrula
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Mechanism of Organizer Action The search for the
"organizer molecule" was one of the first
worldwide biological research programs.
Researchers from Germany, the United Kingdom, the
United States, the Netherlands, Japan, Finland,
Belgium, and China all sort this elusive entity.
http//www.devbio.com/article.php?ch10id123 n
eural induction could occur through a 150 micron
thick, 0.8 micron pore size filter, strongly
suggesting that the inducer was diffusible.
Problems Other tissues could stimulate the
development of Neural Ectoderm Freezing cells
and adding Methylene blue stain causes
induction Molecules found to have organizer
function Follistatin, Chordin, Noggin, Xenopus
nodal-related-3, and Cerberus
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