SEMEN FREEZING

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• Mohak Infertility Center

Our Location
SAIMS Campus,Indore-Ujjain state highway, Near
MR-10 crossing,Indore (M.P.)-453111
Dr. Shilpa Bhandari
 Reproductive Medicine Specialist
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SEMEN FREEZING
Semen freezing is the procedure whereby
spermatozoa are exposed to cryoprotectants and
then cooling them to subzero temperature using
liquid nitrogen. Frozen semen samples can be
stored for many years while maintaining
reasonable parameters of semen. Semen
freezing helps in storage, supply or reserve of
the human sperm for future use. Sperm freezing
is widely used and established method in humans
and other species, it is very effective in
Assisted Reproductive technology (ART) and
fertility preservation in patients with cancer,
before initiation of radiotherapy or
chemotherapy. Semen freezing can be done by two
methods 1. Noncontrolled rate cryopreservation
and 2. Controlled rate cryopreservation.
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CLINICAL APPLICATION OF SPERM FREEZING -
1.Assisted Reproductive Technologies (ART) 2.
Fertility Preservation with Cancer Therapy 3.
Non- malignancy systemic diseases and other
conditions 4. Surgical procedures involving
male genitalia 5. Social and other reasons
ART Assisted reproductive technologies
IUI/IVF/ICSI
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In ART, the most common use of sperm freezing is
in artificial insemination, in vitro
fertilization (IVF), or intra cytoplasmic sperm
injections (ICSI) for various infertile couples.
One of the ART options usually offered to
infertile couples is intrauterine insemination
using fresh or frozen sperm. Although the
technique is used preferably with a fresh semen
sample, the availability of freezing sperm
samples is an option usually offered by
infertility clinics in case the male partner
cannot produce semen. In case of severe male
factor infertility, the samples can be frozen for
later use.
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Fertility Preservation with Cancer Therapy
Another application of sperm freezing is for
cancer patients before initiation of cancer
therapy. The option of sperm freezing should be
offered to any male undergoing chemotherapy or
radiotherapy as these treatments can have
long-term or permanent cytotoxic side effects on
testicular function. One of the advantages of
semen freezing is here is that the frozen sperm
can stand multiple freezing thawing cycles with
no effect on the sperm quality this is
beneficial in cases where patients might have
testicular cancer and require surgical removal of
the whole testis, with no future possibility of
obtaining sperm again. For young males before
puberty , cryopreservation of testicular tissue
may be an option for fertility preservation in
future, improved chemotherapy regimens may give
hope to patients in terms of maintaining their
sexual and fertility potential after therapy, but
at present all male patients diagnosed with
cancer who wish to have children should consider
sperm freezing or cryopreservation of testicular
tissues for further ART use.
Non- malignancy systemic diseases and other
conditions
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Cryopreservation of sperm or testicular tissue
can also be used in patients prior to cytotoxic
therapy for non malignant conditions, such as
autoimmune diseases, kidney diseases,
inflammatory bowel disease and heart transplant
procedures. Most of these conditions are not
fatal and the patients should be offered freezing
of their sperm or testicular tissue prior to the
cytotoxic therapy in order to preserve their
fertility for the future.
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Surgical procedures involving male genitalia
Sperm freezing can also be used prophylactically
before, during, or after certain surgical
procedures as these may have serious adverse
effects on male genital structure and functions.
An example is the varicocele ligation procedure
or reconstructive surgery (e.g. vasovasectomy or
vasoepididmostomy). Sperm freezing may also be
used postoperatively to insure against subsequent
loss of patency of the vas deferens.
Social and other reasons
Sperm freezing could be a mean of preserving
fertility in men with social reasons to preserve
their rights to have children bearing their
names, for example soldiers being deployed to
combat missions in war. Other reasons for sperm
freezing might be immediately pre and postmortem
where relatives of a person wish to ensure that
the person can have a legal heir.
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CONCLUSION
Applications of sperm freezing now days are
diverse and include humans, animals and insects.
Despite the undeniable morphological and
functional adverse effects that cryopreservation
exerts on sperm, it still remains one of the core
methods of fertility preservation for patients
and healthy volunteer donors. Future studies are
expected to concentrate on advancing technology
to achieve the goal of damage free sperm after
freezing. Encouragingly, recent advances in ART
suggest that it will be possible eventually to
achieve a healthy pregnancy and live birth from
freezing of a single sperm or frozen semen
sample. Nevertheless, it has proved to be boon in
the era of modernization helping childless
couples to embrace parenthood. Sperm freezing has
become an accepted modality for fertility
preservation and childless couples.
Dr. Shilpa Bhandari is one of the best IVF
specialists in Indore and provides the
Infertility treatment in Indore at very low cost.
Book an appointment today call now us 78980-
47572 / 80852-77666 for more information. Request
an Appointment / General Inquiry- https//www.mo
hakivf.com/Contact-us.htm
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Post - How does a short luteal phase affect
fertility?
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Contact Details
Mohak Infertility Centre Email-
help_at_Mohakivf.com Phone -78980-47572 /
80852-77666 / 97550-44424 / 0731-4231756 Address
- SAIMS Campus,Indore-Ujjain state highway,Near
MR-10 crossing,Indore (M.P.) Visit our
website- https//www.mohakivf.com for more
information.
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