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Orde van den Prince
Innovatie en Ondernemerschap Hoe goed zijn we
bezig in Europa en Vlaanderen?
Dr Martin Hinoul Business Development Manager,
Technology Region Leuven Lo, 24 mei 2009
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The world became FlatThomas Friedman
60 trillion
Market Value - GDP
year
2000
1900
0.5 bi
1 bi
2 bi
customers
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Challenges ahead for a worlds divided economy
Source The Economist
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(No Transcript)
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The European Technology Dilemma
The technology gap (10 yrs) with the US is still
not decreasing
The technology gap with China and India (20 yrs)
is shrinking every month
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Lisbon 2000

• 70 of the active population should be employed
• 3 of the GDP should be spend on RD
• And Europe should become the strongest Knowledge
  economy in the world

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A nation which depends upon others for its new
basic scientific knowledge will be slow in its
industrial progress and weak in its competitive
position in world trade Science, the endless
frontier Vannevar Bush 1945
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Innovation and Lisbon 2010 New faces It is 5 to
12 !
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The Knowledge Economy Regions are lining up
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Old and New Halls of Fame
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Seattle
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Pittsburg
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San Diego
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Silicon Valley
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Silicon Valley A complex Network of Clusters
Clean Technology
2005 2000 1980 1975 1955 1939
Stanford Fred Terman
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Silicon Valley

• A network and a state of mind (Felix Theeuwes
  Durect Corporation)
• A network effect that transcends national
  boundaries (Wim Roelandts voorzitter Xilinx)
• Regional centers growing together increasing the
  overall Pie (Wim Roelandts Xilinx)

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Professors, ondernemers, rol modellen en venture
kapitalisten
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Knowledge Economy Regions in Asia
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European Knowledge Economy Regions
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The East of England RegionMap of Silicon Valley
inset
Cambridge
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Centre of IP and Deal-flow
Milton Keynes - Fastest Growing Business
City Best Business Universities (e.g.
Cranfield) A UK Leading technology using region
Centre of IP and Deal-flow
Planned East-West Rail
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The Golden Triangle of the UK
the only way to compete is to concentrate
resources in regions that are strong. Martin
Rigby. MD, ET Capital, Cambridge Lecture, 2006
Some 75 of all VC funds found a home here in
2006
Cambridge
Along the M11
O2C Arc IP Ally Huge Brainpower
Stansted and the Herts Pharmas
London Finance and Global Connections (plus
its Universities)
Oxford
Down the A34
Global connectivity
Thames Valley Industry and Commercialisation
Heathrow Growth Area
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• Knowledge economy index
• Economic incentive regime
• Education
• Innovation
• ICT

? Belgium
Source World Bank Institute
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The importance of Innovation

• Innovation is important for economic growth
• 50 since World War II
• 66 in the 90s
• 90 in the 21th century
• Lisbon 2010 Europe should bring the RD effort
  from 2 to 3
• A difficult mission
• ( a shortage of 110 billion Euro and a
  shortage of 700.000 scientists
• and engineers)
• Finland 3,49 Nl 1,94 UK 1,93 Fr 2,2 It
  1,07 Sp 0,97
• Po 0,65 Ro 0,39 Bg 0,47.US 2,8

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Innovation is also changing

• Faster, Faster, Faster
• It requires wider collaboration across
  disciplines and specialties (multidisciplinary)
• The concept of intellectual property is being
  reexamined in the light of these collaborative
  demands
• It requires a wider collaboration of regions
• The trend is towards open innovation
• It requires a triple helix approach

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The Triple Helix

• Is the complex between three
  actors
• The Government
• The Industry
• The Knowledge Centers

"dynamics"
William Baumol The Free-Market Innovation
Machine 2002
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The Triple Helix is based
on
"dynamics"

• Knowledge creation
• Knowledge diffusion
• Knowledge exploitation

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The Leuven ModelKnowledge Transfer and
Collaboration
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Leuven
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(No Transcript)
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The Value Chain

• Knowledge Centers
• Entrepreneurs Role Models
• Money
• Capital Markets
• Infrastructure
• Cluster Policy
• Presence of International Companies
• Networks
• Government
• Quality of Life

Gibbons Saxenian - Hinoul
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Knowledge centersCritical Mass 6 000
researchers

• K.U.Leuven - 3440 researchers
• Gasthuisberg 1300 researchers
• LERU (League of 12 European Research Intensive
  Universities) coördinationcenter
• IMEC 1600 researchers
• VIB Vlaams Instituut Biotechnologie
• Leuven
• 36.500 students (KUL, Groep-T, KH)
• 11 Belgian patents
• 4000 foreign students, 49 nationalities

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Entrepreneurs and Role Models

• Tradition
• Stella 1366 The first biotech Cie
• in Leuven
• Textile industry 14 century
• Vesalius, Lipsius, Rega, Lemaitre, Minckelers,
• Today
• Oosterlinck, Collen, Declerck, Debackere, Van
  Deurzen, Callewaert, Verjans, Van Craen, Peeters,
  Byen, Bijnens, Callaerts, Luyten,
• LMS, ICOS, Telindus, Materialise, Option, JSR,
  Ardatis, Eyetronics, Tigenix, Ubizen,

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Transfer Cell K.U.Leuven RD
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Spin-off companies

• At the moment 63 spin-off companies (exploiting
  university research results) are active, creating
  employment of gt2.200 employees.

• 6 successful IPOs are established

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• K.U.Leuven Research Development received the
• 2008 IPTEC Tech Transfer Award
• Nominated
• K.U.Leuven RD (Winner 2008)
• Columbia University (USA)
• Imperial Innovations (UK)
• MIT (USA)
• Wisconsin Alumni Research Foundation (USA)
• Received the award
• 2006 Stanford University (USA)
• 2007 Tsinghua University (China)

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Money

• RD funds
• KUL 260 mi (90 mi contract research LRD)
• IMEC 265 mi
• Participation in 200 European Programs

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Money

• Seed Capital Venture Capital 300 million

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Capital Markets

• Other capital markets
• IT- Partners, Fortis Private Equity, KBC Investco
• Stockmarket
• Ubizen
• ICOS
• Option
• Telindus
• Quest for Growth
• OMS
• Thrombogenics
• Metris
• Tigenix
• ..

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Infrastructure and Planning

• KUL 500.000 m2 total infrastructure
• IMEC 35.000 m2 total infrastructure
• KUL IMEC 150.000 m2 research space
• II ( Incubator) 5.000 m2 total infrastructure
• Haasrode Research park136 Ha, 5000 jobs
• Campus Remy
• Ubicenter
• Arenberg Research park 13 Ha 2005-2012
• Termunck 36 Ha 2012 - ?

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The Leuven Technology Corridor
II
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K.U.Leuven hospital

• Budget University Hospital
• 640 million
• 1,955 beds
• 63,795 hospitalisations
• 536,478 hospitalisation-days
• 577,861 consultations
• 50,383 emergencies
• (2006)

Hospital
Academic
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IMEC
Imec and the Worlds Largest Industry Commitment
to Semiconductor Research in Partnership
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HAASRODE RESEARCH PARK A full house 5 000 jobs
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MASTERPLAN Arenberg Research Park
D
C
B
A
KCAP Rotterdam
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Arenberg Science Park
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Arenberg Cluster B - ICT
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Bio Incubator
OMS reMYND ReGenesys FORMAC ThromboGenics Fugeia
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Bio-incubator Leuven- verder bouwen aan een
succesverhaal -
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Totaalaanpak triple helix
Bio-incubator I
industry
university
Wetenschapspark Arenberg Sanering van
gronden K.U.Leuven en IMEC Totale project
884.510 euro EFRO-steun 265.353 euro
Pro-actieve spin-off creatie
management K.U.Leuven Research
Development Totale project 520.000
euro EFRO-steun 208.000 euro Agentschap
Ondernemen 234.000 euro
government
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Cluster Policy
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The concept
Region
Economy
Ingredients
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The Old Economy
Region
Economy
Universiteit
Ingredients
INBEV
KBC-groep
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The New Economy
Region
Economy
Ingredients
Companies
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Cluster Formation
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Telematica-communicatie
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Micro-elektronica - nanotechnologie
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E-security

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Life sciences
Thromb-X
reMYND
Tigenix
Dakocytomation
RNA-TEC
4AZA Biosciences
Cochlear
Algonomics
M-Elect
Vivactiss
PatientWeb
Neurogenetics
QMedit
Custom8
PharmaDM
_at_Medical Techn.
Data4S
Oncomethylome
MXS
Diatos
New Standard Eng.
Medicim
Materialise
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Life sciences in Leuven
Kenniscentra
E.S.R.I. Deckers Div
Biotest Seralco Benelux
Dermat
Thrombogenics
Centers of excellence
Terumo Europe
Tigenix
ReMynd
IDT(RNA-TEC)
Dakocytomation
BioTie Therapies Corp.
Norgine
Univ hospitals K.U.Leuven Rega Institute CEHA Lab
of Exp. Genetics Transgenese
Cochlear
Algonomics
M-Elect
Autocyte Europe
PatientWeb
M4S
Medvision Benelux
K.U.Leuven L-MTC
Materialise
Neurogenetics
QMedit
_at_Medical Techn.
MXS
VIB VIGOUR
IVIA
Custom8
Onco Methylome
Puur innovatieve bedrijven
Conti BPC
Fugeia
Regenesys
Diatos
New Standard Eng.
Medicim
Malaiseco
Ortec
Formac Pharmaceuticals
CMPG
Gemengd innovatieve bedrijven
Centocor
VWR International
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Mechatronica
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Feed-food-health
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A Powerful Advantage for our Region
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Cluster policy Leuven
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12 Lessons from Leuven

• Basis is a critical mass of high quality research
• Create an appropriate entrepreneurial climate in
  a university context
• Create a legal framework with respect to
  exploitation of academic research
• Clear incentives and policies to encourage
  research groups and departments to actively seek
  knowledge transfer opportunities
• Create a professional Interface Unit An
  Integrated approach on research valorisation
  multidisciplinary team high value services
• Create a Seed Capital and/or Venture Capital Fund

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12 Lessons from Leuven

• Foster spin-offs from your university research
• Clear ownership of Intellectual Property
• Improving awareness among federal, regional and
  local shareholders
• Supporting a forum for business, academia,
  government and supporting organisations to build
  partnerships by sharing new ideas and best
  practices. Importance of the networks.
• Focus on Focus and Enthusiasm
• Quality of life

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Quality of Life
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THE EINDHOVEN -LEUVEN - AACHEN TRIANGLE
A European Top Technology Region
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A European Region with Critical Mass
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• 155 miljard (2007 est. MH)
• 53 000 toegevoegde waarde/werknemer

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A Region with the right ingredients

• Knowledge Centers
• Entrepreneurs Role Models
• Money
• Capital Markets
• Infrastructure
• Cluster Policy
• Presence of International Companies
• Networks
• Government
• Quality of Life

Quality of life
Capital Markets
Infrastructure
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Knowledge Centres
Knowledge Centres
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IndeedA European Region with top Universities
and State of the Art Research Centers
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Close to the 3 Lisbon target ?
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Infrastructures
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IndeedA European Region with State of the Art
Research and High Tech Parks
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High Tech campus Eindhoven
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The Leuven Knowledge Pearl
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IMEC In Leuven and the Holst Centre In
Eindhoven A Close Coöperation
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The DSM Chemelot High Tech Campus
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RWTH Aachen Campus

• 15 Cluster
• 10.000 new jobs
• 2 billion investment

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What about the other ingredients?

• Entrepreneurs Role Models
• Money
• Capital Markets
• Cluster Policy
• Presence of International Companies
• Networks
• Government
• Quality of Life

Capital Markets
Infrastructure
Infrastructure
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The DSP Valley The Broadband Hub in Europe ?
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LIFE SCIENCES MEDISCHE TECHNOLOGIE
Specialisatie en pieken Selectie en typologie
belangrijkste actoren
TTR Nederland
LifeTec Network
TTR België
FlandersBio
Helvoet Pharma
Technomed
Life Sciences Limburg (LIOF)
Life Science Platform
Tosoh Bioscience
Supra Polix
Kenniscentra en centers of excellence
Kingfisher Healthcare
Occam
Philips Medical Systems
Thromb-X
OncoMethylome
Pamgene
Spronken Orthopedie
Medtronic
BioLiege
Neurgenetics
KUL
Healthcare Technology Knowledge Network
Pie Medical
VIB
AZ Maastricht
Pure innovatieve bedrijven
Medinvest
BIOMED
Ortec
KUleuven
Blue Medical
U Maastricht
U Hasselt
Silicos
Imec
TU Eindhoven
Akzo Nobel/ Organon
UZ Leuven
U Hasselt
Centocor
Pharma Neuro Boost
IMEC
U Luik
Kath. FH NRW
BioWin
Terumo Europe
Forschungszentrum Jülich (IME)
RWTH Aachen
Human Health
DSM
Notox
UK Aachen
Abiomed Europe Gmbh
Mixed innovatieve bedrijven
Dräger Medical
Activ Care transcon Gmbh
Grünenthal
Spectaris
DASGIP AG
Bioriver Life Science Cluster
Pharma Aldenhoven
LifeTec Aachen-Jülich
Trommsdorff
Tri-nationale MaasRijn triangle cluster
MetNet NRW
TTR Duitsland
Netwerken
Bundesverband der Pharmazeutischen Industrie e.v.
(BPI)
Aachener Kompetenzzentrum Medizintechnik AKM
Alma-grid LSMT samenwerkingsproject Luik,
Hasselt, Maastricht, Aken Heartbeat INTERREG
III initiatief MaasRijn triangle
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HIGH TECH SYSTEMS MATERIALENSpecialisatie en
pieken Selectie en typologie belangrijkste
actoren
Nederlandse Vereniging voor Precisie-technologie
DSP Valley
Sirris
TTR België
Vereniging van de Nederlandse Chemische Industrie
TTR Nederland
Walonie Espace
DAF
nv Graco
FMTC (mechatronica)
Siemens VDO
Vista nv
Kenniscentra en centers of excellence
Alro Holdings
Philips
Ford Werke
Chemelot
Bosch Packaging
Bosch Hydraulic
LAG Trailers
Borealis Polymers
FLAMAC (materialenonderzoek)
Akzo Nobel
Netherlands Aerospace Group (NAG)
Epiq
Campus Geleen
KUL
Nedcar
Pure innovatieve bedrijven
DOW Belgium
Imec
KUleuven
Spaas Kaarsen
Vanderlande Industries
Philips
ATC Eindhoven
DSM
Imec
U Hasselt
Agoria
Campus Eindhoven
U Hasselt
U Luik
ASML
Tessenderlo chemie
U Luik
Fraunhofer Institut
Nederlandse vereniging voor rubber en kunststoffen
Heraeus Electro-Nite International
Forschungszentrum Jülich
Océ
Stork food systems en printing
RWTH Aachen
Hochschule Niederrhein
Continental
Schumag AG
Oerlikon Textile
Mixed innovatieve bedrijven
Flanders Drive
Philips (licht)/ Philips Onderzoeksinstituut
Siempelkamp
Cerobear
Trützschler
Pierberg
Scheidt Bachmann
Prüfcentrum Siemens transportation Systems
Verband der Chemischen industrie (VCI)
FEV Motorentechnik
Voith Paper
Verband der Elektrotechnik (VDE)
3M
AUNDE
Cluster Chemie/ Kunststoffe Mitteldeutschland
Munters Euroform
Netwerken
CAR e.V.
TTR Duitsland
Verbundinitiative Automobil Nordrhein-Westfalen
(VIA NRW)
INTRA e.V.
Internationaal netwerk Automotive.net
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FOOD NUTRITIONSpecialisatie en pieken
Selectie en typologie belangrijkste actoren
Regio Uden-Veghel
Foodregio Helmond e.o./ Greenport Venlo
TTR Nederland
Flanders FOOD
TTR België
Interbrew
Flora Holland
Farm Frites Belgium
Kenniscentra en centers of excellence
FEVIA
Foodvalley regio Wageningen
Veiling ZON
SES Europe
Nutreco
Tropicana Looza
Wessanen
Rendac
Lambrechts nv
Better3Fruit
Newtrition
Choprabisco
Orafti Group
Food Nutrition Topinstituut
Veiling Haspengouw
Masters Food
Pure innovatieve bedrijven
U Maastricht
KUL
Nedalco
Hercules Europe
KUleuven
HAS Den Bosch
Imec
Proefcentrum Fruitteelt vzw
DMV Campina
Unilever
Tiense Suiker
Scana Noliko
U Wageningen
U Hasselt
U Luik
Numico
Fontys
Food Concortium
HochSchule Niederrhein
Provinciaal Overleg Regio Tienen
IncoPack
Heineken
Citrique Belge
Frauenhofer Gesellschaft
Sovion
Food Connection Point
Zentis
KronenBrot KG
Mixed innovatieve bedrijven
Chocoladefabriken Lindt
Leuchtenberg
Carl kühne FG
Nestle Deutschland
Cargill
Deutsche Landwirtschaft Gesellschaft (DLG)
Landgard
Food Processing Initiative
Zuckerfabrik Jülich
Walter Rau Neusser Öland
Netwerken
Agrobusiness
Deutsches Institut für Lebensmitteltechnik
TTR Duitsland
Bundesvereinigung der Deutschen
Ernährungsindustrie
Foodcity
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Some facts and figures for the ELAt Triangle

• Source Policy Research, Hochschule
  Niederrhein, Etil.
• 155 billion - 2,8 million active population
  or 1 out of 5 jobs HAV-(est. MH)

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A Powerful Advantage for our Region