Title: Water maze place learning: All animals no treatment
1Water maze place learning All animals (no
treatment) Escape latency across blocks of 4
daily trials
2Drug Probe Test 1 mg/kg Scopolamine (odd rats)
or Saline control (even rats) Quadrant Time
(3 target)
3Drug Probe Test 1 mg/kg Scopolamine (Odd rats)
or Saline control (even rats) - Preference score
(based on quadrant time).
4Drug Probe Test 1 mg/kg Scopolamine (Odd rats)
or Saline control (even rats) Annulus crossings
(1 goal)
5Drug Probe Test 1 mg/kg Scopolamine (Odd rats)
or Saline control (even rats) - Time in annulus
(2x platform diam)
6Drug Probe Test 1 mg/kg Scopolamine (Odd rats)
or Saline control (even rats) Proximity measure
7Drug Probe Test 1 mg/kg Scopolamine (Odd rats)
or Saline control (even rats) Proximity measure
8Drug Probe Test 1 mg/kg Scopolamine (Odd rats)
or Saline control (even rats) Latency to enter
Annulus
9Reversal Test (drug-free) 7 days following probe
test platform relocated to diagonally opposite
quadrant Escape Latency
10Reversal Test (drug-free) 7 days following probe
test platform relocated to diagonally opposite
quadrant Escape Latency (squad 1 removed
different injection needles)