Biochemistry 511

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Biochemistry 511 Spring 2006 Instructor Dr.
Elizabeth Gross 742A Biosciences 292-0480
gross.3_at_osu.edu
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TA Yuwen Dai (Elaine) Office 814
Biosciences Office hours T-R 10-11
dai.32_at_osu.edu
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Text Horton Biochemistry 4th Edition
Prentice-Hall, 2006 Web site http//www.biosci.o
hio-state.edu/ bioch212/biochem511/
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Grading 2 Midterms 30 each 1 Final -
30 Quizzes - 10
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Schedule See syllabus.
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• Review of organic and biochemistry.
• A. Organic molecules functional groups
• B. Forming biopolymers
• C. Amino acids proteins
• D. Carbohydrates
• E. Nucleotides and nucleic acids
• F. Lipids and membranes.
• Life, energy and the laws of thermo-
• dynamics.

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A. Organic molecules functional groups.
R alkyl chain.
Organic compounds carbon skeleton
functional groups.
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CO2
-H
Reduced -----------------------------?oxidized
Stores energy Energy
released
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B. Forming biopolymers.
Many biological molecules exist as polymers.
M
M

H- -OH H-
-OH
M
M
H-
-OH H2O
Dehydration synthesis requires energy
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M
M
H-
-OH H2O
M
M

H- -OH H-
-OH
Hydrolysis releases energy
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C. Amino acids proteins.
Amino acid
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Dipeptide
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Proteins Enzyme - lysozyme
Active Site
Substrate in the Active site.
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D. Carbohydrates Monomers sugars
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Monosaccharide glucose
alpha
beta
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D.
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E. Nucleotides and nucleic acids.
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Deoxyribose
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ATP - adenosinetriphosphate
Energy currency of the cell
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Bases Genetic code
Sugar posphate backbone
DNA
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DNA molecule
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Phospholipids
F. Lipds membranes
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