Nonclassical vitamin D functions

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Non-classical vitamin D functions

• Biochemistry 511
• Fall 2009
• Dr. Colleen E. Hayes
• Department of Biochemistry
• University of Wisconsin
• Madison, Wisconsin USA

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Solar radiation catalyzes vitamin D3 synthesis
Calcitriol
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Sites of 1,25-dihydroxyvitamin D3 synthesis
Kidney
Testes
Brain
Anderson et al. 2008 Mol Cell Endocrinol 2851
Prostate
Lung
Jejunum
Femur
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Vitamin D and cathelicidin
Liu and Modlin 2008 Cur Opin Immunol 20371
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Multiple sclerosis(MolecularMovies.org)

• http//www.livingpixels.net/ms.html

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Discussion Groups (revised)

• Vitamin D hormone in skin, wound healing,
  reproduction and cardiovascular health
• Vitamin D hormone and cathelicidin
• Vitamin D hormone and multiple sclerosis