HISTORY OF RECOMBINANT DNA

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HISTORY OF RECOMBINANT DNA
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IN THE BEGINNING

• 1928 DNA transformation discovered by Griffith
• 1970 Restriction enzymes and reverse
  transcriptase
• 1972 Berg achieves gene splicing
• 1973 Cohen, Change, Helling and Boyer create
  biologically active plasmid DNA
• 1975 Southern blotting invented
• 1977 Gilbert and Sanger develop a way to sequence
  DNA
• 1988 Terry Mullis invents PCR using DNA
  polymerase from Thermus aquaticus (Taq)
• 2000 First human genome draft completed
• http//www.molecular-biologist.com/