College of Medicine Faculty Council

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College of Medicine Faculty Council
November 6th, 2001
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Alistair Webb College of Veterinary Medicine 392
4700 X3828 webb_at_ufl.edu
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The battle for the program still lies ahead
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IACUCS ROLE
represent societys concerns regarding the
welfare of animal subjects
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USDA gt Animal Welfare Act rabbits major
mammals
PHS gt OLAW gt The Guide any vertebrate
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UF has 3 IACUCs

• 01 HSC
• 02 IFAS
• 03 CLAS

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UFS ASSURANCE to OLAW
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DUTIES

• semi-annual review of program
• biannual inspection of facilities
• report to IO major and minor
• deficiencies justify deviations
• review complaints and reports of
• non-compliance

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DUTIES Cntd

• make recommendations to IO on program,
• facilities and personnel training
• review and approve, require modifications,
• or withhold approvals of proposed animal
  use
• suspend non-compliant activities involving
• animals

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DUTIES Cntd

• make recommendations to IO on program,
• facilities and personnel training
• review and approve, require modifications,
• or withhold approvals of proposed animal
  use
• suspend non-compliant activities involving
• animals

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THE 3 Rs
REPLACEMENT REDUCTION REFINEMENT
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THE PROCESS
Development Screening Member Consideration Designa
ted Reviewer or Convened meeting aka Full
Committee
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DEVELOPMENT
forms on the web AV involvement
IACUC Office
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(iv) Procedures that may cause more than
momentary or slight pain or distress
to the animals will (A) Be performed
with appropriate sedatives, analgesics or
anesthetics, unless withholding such
agents is justified for
scientific reasons, in writing, by the principal
investigator and will continue
for only the necessary period of time
(B) Involve, in their planning, consultation
with the attending veterinarian
or his or her designee (C) Not
include the use of paralytics without
anesthesia (v) Animals that would otherwise
experience severe or chronic pain or
distress that cannot be relieved will be
painlessly euthanized at the end of the
procedure or, if appropriate, during the
procedure
9 CFR 2.31.d.iv
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SCREENING
correctness of form disposition
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FC
DR
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MEMBER CONSIDERATION
after AV consulted 5 working days concerns?
advise DR
refer FC
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DESIGNATED REVIEWER
appointed by Chair approves
modifies refers
APPROVABLE
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DESIGNATED REVIEWER
time table set by FC 1 week gt reminder 2
weeks return to office 6 weeks gt withdrawn
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CONVENED MEETING
protocols available 5 working days half members
quorum 1 2 reviewers
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CONVENED MEETING
approve approve with modifications table disapprov
e
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APPROVABLE gt APPROVED
signed hard copy to office electronic copy
provided
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REVIEWING ELECTRONIC PROTOCOLS
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MS Word 2000 exchange comments via e-mail
attachments
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How the Investigator reads the comment
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Find the yellow blocks hover
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(No Transcript)
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DOs and DONTs
Visit the web site
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Do
down-load latest form
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Do
read follow the instructions
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Do
complete the form yourself
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Do
remain in compliance
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incorporate flexibility follow protocol keep to
numbers allowed dont keep animals in lab check
animals daily seek veterinary advice early PI is
the responsible person
show compassion for your animals
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Dont
expect miracles
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Dont
procrastinate
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Dont
cut and paste your grant
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Dont
be technical in the lay language section
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Dont
create subject numbers
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IRB vs IACUC
subject numbers details of what happens to
subjects no need for ICF no conflict of interest
issues
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Ways to Create Investigator-friendly interaction
and speed up the process
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dichotomy animals science remember we are all
colleagues do our homework respond promptly speed
limits the law
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? SOPS
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(No Transcript)