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P1252108902lFGdR

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software including HKL2000, O, COOT, CCP4, PHENIX. AKTAbasic Coupled to MALS ... Absolute mass from Wyatt multi-angle light scattering mini-DAWN instrument and ... – PowerPoint PPT presentation

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Title: P1252108902lFGdR


1
Crystallization and Imaging
Robotics -with funding through the HEA, we have
established Irelands first high-througput
robotics facility, with the capability for
nanolitre sitting and hanging drops
  • Protein Overexpression
  • INFORS multi-level shakers
  • for Litre scale E.coli, sidebar
  • cooling for temp control
  • -future expansion of insect
  • cell expression facilities
  • AKTAbasic Coupled to MALS
  • Milligram scale protein purification
  • Absolute mass from Wyatt multi-angle light
    scattering mini-DAWN instrument and Optilab
    Refractometer detects oligomeric states and
    heterogeneity of proteins and complexes
  • -ability to measure the second virial
    co-efficient of proteins

X-ray Facility -complete Rigaku/MSC,
MicroMax-007, R-axis IV, X-stream
2000 -computational facilities include SGI and
linux boxes, stereographic hardware, standard
software including HKL2000, O, COOT, CCP4, PHENIX
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