Prsentation PowerPoint

1
Introduction
Advanced Course on Bioinformatics and Comparative
Genome Analysis
Fredj Tekaia Institut Pasteur tekaia_at_pasteur.fr
2
Advanced Course on Bioinformatics and Comparative
Genome Analysis June 30 - July 12,
2008 Universidade Federal de Santa Catarina,
Florianopolis, Brazil Organizers/Contact
Alberto M.R. Davila, Instituto Oswaldo Cruz,
FIOCRUZ, Rio, Brazil Edmundo Grisard,
Universidade Federal de Santa Catarina,
Florianopolis, Brazil Hugo Naya, Institut
Pasteur Montevideo, Uruguay Fredj Tekaia,
Institut Pasteur Paris, France.
Course web page http//www.pasteur.fr/tekaia/ACB
CGA.html
3
Financial support
CNPq/QUADTRYP/FINEP
4
Why this course ?
5
Complete genomes 3823 projects 819 published
(12-06-08) 1848 Bacteria 90 Archaea
936 eukaryotes 130 metagenomes
672
53
Tree of life
3 phylogenetic domains Lifestyles
mesophiles (hyper)thermophiles psychrophiles
extreme conditions,...
94
http//www.genomesonline.org/
6
Number of available completely sequenced genomes
3823 projects
06-2008
Completely sequenced Genomes that span the three
domains of life are growing at a rapid rate
List and references
GOLD
7
Genome studies show that Access to entire
genome sequences is revolutionizing our
understanding of how genetic information is
stored and organized in DNA, and how it has
evolved over time. The sequence of a genome
provides significant details of the gene
catalogue within a species. Comparisons of
complete genome sequences show the acceleration
in the understanding of species organisation,
links between genes, functions of the genes,
evolution of genes, genomes and species.
gt Beyond fundamental biological and
methodological interests, Expected applications
include Drug, Medical and Agricultural,
discoveries.
8
Few scientists are involved in generating data
and much more are involved in data analyses
9
Genomics
Is the study of genomes. (including the study of
their genes, proteins, their sequences,
functions, evolution,....)
10
Bioinformatics is needed to transform the flood
of raw data (sequences) into scientific knowledge.
11
(No Transcript)
12
Bibliography
13
(No Transcript)
14
Bioinformatics and Comparative Genome Analysis
The main objectives of the course are to
familiarize you with bioinformatics and large
scale genome data analyses skills by
introducing 1- advanced fundamental algorithms
in Bioinformatics 2- their application in
genome analyses 3- recent knowledge acquired
from genomes studies and their perspectives.
15
(No Transcript)
16
(No Transcript)
17
We hope that this course will motivate some of
you to continue their involvement in these
fascinating domains Bioinformatics and Genomics.
18
Enjoy this exiting program and your stay in
Florianopolis.