Catabolism

1
Catabolism

• Anaerobic respiration
• C6H12O6 NO32-

26 ATP CO2 NO2- ...
Glucose nitrate
energy carbon nitrite
Final electron acceptor
for use dioxide
or CO3 2-(carbonate) or SO42- (sulfate)
2
Anaerobic respiration

• Steps
• . Glycolysis
• . Gateway or Preparatory step
• . Krebs or TCA (tricarboxylic acid) or Citric
  acid cycle
• . Electron transport chain and chemioosmosis

3
Electron transport chain
Pg. 130
Pg. 130
4
NADH2
1 NADH2 2ATP
1 FADH2 1ATP
FADH2
4
Catabolism

• Fermentation
• C6H12O6

2 ATP fermentation products
glucose
ex. acids, gases, alcohol, acetylmethylcarbinol
(acetoin),
5
Fermentation

• Steps
• 1. Glycolysis
• 2. Formation of the fermentation products
• substrate phosphorylation only, no oxidative

6
2. Formation of the fermentation products
Pyruvic acid is the final electron acceptor
7
Integration of metabolism

• Many chemicals can be used for catabolism using
  glycolysis, the Gateway or preparatory, or Krebs
  cycles
• other carbohydrates
• proteins
• fats (lipids)

8
Integration of metabolism

• The same pathways can be used in anabolism to
  build molecules
• amphibolic pathways used in both catabolism and
  anabolism

9
Integration of metabolism
Pg. 137