Exam

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Exam please check registrars final version
of the exam schedule 180 minutes 120
multiple choice questions-120 points -4 short
answer question-60 points multiple
choice-lecture 7a onwards short answer-whole
term
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Nutrition care plan Due on time please-if
problems please ensure I know in advance
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Lecture 11a 28 MARCH 2011   Arthritis and
Dermatitis
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Osteoarthritis (OA)   -swelling of the
joints   -overweight causes wear of
cartilaginous surfaces   -such wear results in
loss of chondroitin sulphate and glucosamine
which are carbohydrate polymers
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Rheumatoid arthritis (RA)   -autoimmune attack
that in part involves loss of chondroitin
sulphate and glucosamine
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Nutrition approaches to Arthritis   -appropriate
nutrition may prevent weight gain thus avoiding
that cause of osteoarthritis  
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Nutrition approaches to Arthritis nutraceuticals
-chondroitin sulphate   -glucosamine   -bot
h of these nutraceuticals are meant to
replace lost chondroitin sulphate and
glucosamine                                 
              -both readily available OTC and
are useless
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Nutrition approaches to Arthritis nutraceuticals
-fish oils reduce arachidonic derived
pro-inflammatory eicosanoids while producing
anti-inflammatory eicosanoids in RA but not OA  
-evening primrose oil, blackcurrant oil,
and borage oil reduce arachidonic derived
pro-inflammatory eicosanoids while producing
anti-inflammatory eicosanoids in RA but not OA  
-review pathways involved for nutraceutical
oils
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Class activity-what is the best nutritional
approach to arthritis? Why?
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Dermatitis   Atopic (eczema)   -skin
inflammation that is due to an
immune response   -can be due to a food
allergy   -solution -avoid allergen
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Dermatitis-nutraceutical -fish oils reduce
arachidonic derived pro-inflammatory eicosanoids
while producing anti-inflammatory eicosanoids  
-evening primrose oil and borage oil
reduce arachidonic derived pro-inflammatory
eicosanoids while producing anti-inflammatory
eicosanoids   -as with RA many of these
trials include subjects that are on
anti-inflammatory prescribed drugs- what is the
impact of this?
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Dermatitis Sebborheic (scaly) -can be due to
biotin deficiency   avoid biotin
deficiency   - can be due to riboflavin
deficiency   avoid riboflavin deficiency  
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Scaling eczema-like dermatitis   -can be due to
linoleic or a-linolenic acid deficiency -this
may be a problem with long term TPN  
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Nutritional remedy for dermatitis (types above)
in general   -topical application of retinoids
(similar in structure to vitamin A)   -reduces
dermatitis   -avoid linoleic or a-linolenic acid
deficiency
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Dermatitis herpetiformis   -causes
skin lesions pruritic-itching  
vesicular-vesicles  
papular-solid elevation of the skin  
- all of these lesions are consistent with
coeliac disease and are relieved by a
gluten-free diet