Supercritical fluid methods

1
Supercritical fluid methods

• Jirí Konecný
• 2005

2
Sample is solid phase
3
CFE - Supercritical fluid extraction
Sample
Extraction cell
Oven
4
SFC - Supercritical fluid chromatography
5
Why use supercricitcal methods?
density g/ml Difuzion coeficient dinamic viscosity coeficient presure
GC 0,2 10-5 10-1 0,5-2 MPa
CFC 600 10-8 10-4 to 65 MPa
LC 800 10-9 10-3 10-40 MPa
Propertis of medium are difrent. Sample is better
elution.
6
Using
Analytical chemistry search for new substance
and analyzes concaminans in eviroments
Industry izolation of parfume and special
substaces in famakology
7
Information sources

• Lecture analytical chemistry by Prof. RNDr.
  Sommer, DrSc
• Prof. RNDr. Sommer, DrSc Základy analytické
  chemie
• www.ashlandanalytical.com/ tour-sea.htm
• http//www.pioneerherbs.com/super_critical.htm