Virilism

1
Virilism

• By Tori Boyle and Ian Woodbine

2
Virilism

• Virilism is the development of male secondary sex
  characteristics caused by male sex hormones,
  called androgens, excessively produced by the
  adrenal gland. This disorder can occurs mostly
  in women later on in life due to an excessive
  production of testosterone.

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Glands Affected

• The adrenal glands are the glands affected when
  one has the disorder of virilism. The adrenal
  glands are two small structures that lie on top
  of the kidneys. The adrenal glands produce many
  hormones that regulate body functions including
  androgens, or male hormones such as testosterone.
  Androgens are produced in normal girls and women,
  but are not as heavily produced as in a males
  body. When the adrenal glands become large or
  overactive, excessive androgens are produced,
  creating masculine characteristics in women.

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Hormones

• Androgens- usually a steroid hormone, that
  stimulates or controls the development and
  maintenance of male characteristics in
  vertebrae's.
• Aldosterone A hormone secreted by the adrenal
  glands that is important for maintaining salt and
  water balance in the body.
• Cortisol- A steroid hormone secreted by the
  adrenal cortex that is important for maintenance
  of body fluids, electrolytes, and blood sugar
  levels.
• An imbalance of androgen hormones, caused by the
  enlargement of the adrenal glands, produces
  excessive amounts of testosterone in females.
  The enlargement of adrenal glands is called
  congenital adrenal hyperplasia and is usually
  developed at birth or in the womb.

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Congenital Adrenal Hyperplasia and Virilization

• This is a genetic disorder characterized by a
  deficiency in the hormones cortisol and
  aldosterone and an over-production of the hormone
  androgen. This is caused by an enzyme
  deficiency. Because cortisol production is
  impeded, the adrenal gland instead overproduces
  androgens (male steroid hormones). The
  over-production of androgen causes an over
  production of the male hormone called
  testosterone. Testosterone is a steroid hormone.

6
Females and Virilism

• Women with adrenal virilization may develop
  facial hair. Their menstrual cycles are
  infrequent or absent. They may also develop a
  deeper voice, a more prominent Adam's apple, and
  other masculine signs.

7
Treatment

• There is no cure for virilism, meaning that once
  the disorder takes place in the adrenal glands,
  the glands cannot return the body to normal
  homeostasis levels. Some girls get surgery to
  remove the male body parts or are treated with
  daily doses of a glucocorticoid.
• Glucocorticoid A hormone produced by the
  adrenal gland this hormone leads to an increase
  in blood sugar and creation of sugar molecules by
  the liver.

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Diagrams and Pictures
9
Diagrams and Pictures
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Work Cited

• http//www.google.com/imgres?qvirilismimagesum
  1hlensafeactivesaNtbmischtbnid2u2yJRWosA
  nMaMimgrefurlhttp//60med.ru/Zdorove/Budem-zdor
  ovyi/Gipertrihoz.htmldocidbzrre2GXNB7QyMimgurl
  http//60med.ru/images/stories/2525D02525B72525
  D02525B42525D02525BE2525D12525802525D02525B
  E2525D02525B22525D125258C2525D02525B5/virili
  sm.jpgw300h361eiWNxxT6beNMSU0gGmgOXLAQzoom
  1iacthcvpx118vpy73dur188hovh246hovw205
  tx95ty127sig115200934430124775217page2tbn
  h131tbnw109start21ndsp26ved1t429,r13,s
  21biw1280bih611
• http//medical-dictionary.thefreedictionary.com/ad
  renalvirilism
• http//www.google.com/imgres?qadrenalglandum1
  hlensafeactivetbmischtbnidYGn0-QupN8Gp-Mi
  mgrefurlhttp//www.tuberose.com/Adrenal_Glands.ht
  mldocidw_9HpGgMmy92eMimgurlhttp//www.tuberose
  .com/Graphics/adrenal.jpgw348h300eiiuFxT7roC
  aHg0QGJ_dW0AQzoom1iacthcvpx489vpy278dur6
  56hovh208hovw242tx113ty157sig11520093443
  0124775217page1tbnh130tbnw157start0ndsp1
  8ved1t429,r8,s0biw1280bih611
• http//www.google.com/imgres?qvirilismum1hlen
  safeactivetbmischtbnidFljsfWJ3pOs9uMimgref
  urlhttp//www.pathology.leedsth.nhs.uk/dnn_bilm/E
  ndocrinology/Sexhormonesfertility/FemaleVirilism.a
  spxdocidmE4WMOMaT-IjhMimgurlhttp//www.patholo
  gy.leedsth.nhs.uk/dnn_bilm/Portals/0/f-viril3.gif
  w600h489eiTUp0T7ipAafj0QHGx9WAAwzoom1iact
  hcvpx545vpy158dur2485hovh203hovw249tx1
  51ty86sig104250390964695140691page1tbnh164
  tbnw201start0ndsp18ved1t429,r2,s0biw1
  440bih719

11
Work Cited

• http//www.google.com/imgres?qvirilismum1hlen
  safeactivetbmischtbnidnoc-c3TgA3zWaMimgref
  urlhttp//www.netterimages.com/image/3577.htmdoc
  id1BmfvKZeY6OPWMimgurlhttp//www.netterimages.c
  om/images/vpv/000/000/003/3577-0550x0475.jpgw475
  h550eiTUp0T7ipAafj0QHGx9WAAwzoom1iacthcvp
  x786vpy318dur1125hovh242hovw209tx122ty
  128sig104250390964695140691page1tbnh172tbn
  w149start0ndsp18ved1t429,r9,s0biw1440
  bih719
• http//trialx.com/curetalk/wp-content/blogs.dir/7/
  files/2011/05/diseases/Adrenal_Virilism-3.jpg