PLEURAL LESIONS

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• PLEURAL LESIONS

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Inflammatory Pleural Lesions
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MESOTHELIOMA

• Rare tumor,
• 50 of cases are related to occupational exposure
  to asbestos for 25-40 ys.
• Shipyard workers, miners and insulator.
• Living near asbestos factory or being relative of
  an asbestos workers.
• Latent period 25-40 y.

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Pleural Plaque
Microscopically, the fibrous pleural plaque is
composed of dense layers of collagen
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Mesothelioma
The dense white encircling tumor mass is arising
from the visceral pleura and is a mesothelioma.
These are big bulky tumors that can fill the
chest cavity.The risk factor for mesothelioma is
asbestos exposure. However, mesothelioma is rare
even in persons with asbestos exposure.
Asbestosis more commonly predisposes to
bronchogenic carcinomas, increasing the risk by a
factor of five. Smoking increases the risk for
lung cancer by a factor of ten. Thus, smokers
with a history of asbestos exposure have a risk
50 fold greater likelihood of for developing lung
cancer.
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Mesothelioma
Mesotheliomas have either spindle cells or plump
rounded cells forming gland-like configurations,
as seen here at high power microscopically. They
are very difficult to diagnose cytologically.
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Asbestosis
This is the causative agent for asbestosis. This
long, thin object is an asbestos fiber. Many
houses and offices still contain building
materials with asbestos, particularly insulation,
so care must be taken when doing remodelling or
reconstruction.
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THANK YOU
GOOD LUCK DR.EMAN EMAM