Title: Applications of Nuclear Instruments and Methods
1Applications of Nuclear Instruments and Methods
Nuclear Medicine Diagnostics
2Nuclear Magnetic Resonance Imaging (MRI)
- 1.5T, Master
- Q-Body Coil
- 3D T1-FFE
- Low-high profile order
- 50 x 1.6 mm slices oc.
- 512 x 196 matrix
- FOV 400 x 320 mm
- TE / TR 1.3 / 5.0 ms
- WFS 0.9 pix ( 62 kHz)
- Flip 3518 seconds Breathhold
- 30 cc Gadolinium _at_ 2cc/sec.
18 Second MRI image!!
3Radiation Detectors for Medical Imaging
Positron emission tomographic slice through
patients brain
Positron e (anti-matter) annihilates with
electron e- (its matter equivalent of the same
mass) to produce pure energy (photons, g-rays).
Energy and momentum balance require back-to-back
(1800) emission of 2 g-rays of equal energy
g detectors (NaI(Tl))
4Positron Emission Tomography
Positron emission tomographic image of the heart
After administration of radioactive water H217O
to blood flow, after infarct episode? blood flow
After administration of radioactive acetat
11CH3COOX ? metabolism
Loveland, Morrissey, Seaborg
5DNA Analysis
DNA sample decomposed into single strands, cut
by enzymes into pieces, use electrophoresis to
separate according to size,React separated
segments with radio-labeled probe protein
sequences,identify by auto-radiography
6Applications of Nuclear Instruments and Methods
Nuclear Medicine Therapy
7Nuclear Batteries with Really Long Lifetimes
Nuclear battery a radioactive source placed
inside a capacitor emits a particles, which build
up an electric charge on the plates, or deliver
an electric current. Such batteries can operate
for long durations, a major fraction of a century
(e.g., t1/286 a) and can be made small enough to
be used in implant pace makers.
8Cancer Treatment with Neutrons
Patient treatment station
Cyclotron accelerates protons, which generate a
well defined secondary beam of neutrons with
variable energy and range in tissue.
Treatment success rates of neutron and gamma
irradiation
9Radio Therapy
Heavy-Ion Radio-Therapy Non-Intrusive Brain
Surgery
Heavy ions (here 12C) have a well-defined range
in materials. They lose much of their kinetic
energy shortly before complete stopping, leading
to a radiation dose concentrated at the end of
their range. This provides a non-intrusive
surgical tool
12C Beam 12GeV