Energy Transfer in the Body

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Energy Transfer in the Body

• Chapter 6

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Energy SystemsPower vs Capacity
Max Power Max Capacity Moles/min Total
Moles
ATP-CP 3.6 0.7
Anaerobic Glycolysis 1.6 1.2
Aerobic 1.0 90.0
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Efficiency of ATP Resynthesis

• Substrate-level phosphorylation 30
• Oxidative phosphorylation 40 to 50
• Energy not conserved is released as heat

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Regulation of Energy Metabolism

• Compounds that either inhibit or activate enzymes
  at key control points in the oxidative pathways
  modulate regulatory control of glycolysis and the
  citric acid cycle
• Greatest effect exerted by ADP levels
• Regulators are redundant

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Regulation of Fat/CHO Use

• Fat use is related to FFA concentration in plasma
• Regulators that increase lipase activity increase
  fat use
• Epinephrine, norepinephrine, glucagon increase
  fat mobilization
• Lactic Acid Insulin decrease fat mobilization