Title: Perspective of
1Perspective of Periventricular Leukomalacia
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3PVL?? PVL??????
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8 ??????????2????????????????????????MRI??????239??
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110? PHP 5 PVL 99 PHPPVL 6
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PVL??
PVL
1989-1993
1994-1998
206
250
40 (16)
28 (10)
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?? I? II? III? IV/V?
n203 n25 n31 n27 n9
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28??????????
Disorganized pattern
AF3-C3 C3-O1 AF4-C4 C4-O2 AF3-T3 T3-O1 AF4-T4 T4-O
2
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33PVL????????
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35PVL????????
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41???PVL???????
ASA??????CSA?????
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43PVL????????
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44PVL????????
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46PVL??????????????
47PVL??CO2??
48PVL??CO2??
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50PVL??CO2??
51PVL??CO2??
52PVL??CO2??
53PVL??CO2??
54PVL??CO2??
55PVL??CO2??
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59PVL???????
60PVL???????
61PVL???????
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64PVL???????????
65PVL???????????
SNAP Score for Neonatal Acute Physiology
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66PVL???????????
67PVL???????????
68PVL???????????
SNAP?????PVL?????????????????????????????????????
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69PVL??????????
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e?????????????????????????creatinine???????
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70PVL????????
71PVL??????
72PVL??????
73PVL??????
PVL????????APGAR score???? PVL?????????????? ??
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??PVL????????????????????????? PVL?????????CAM???
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75 ?????????(PVL)?????????????????flip
flap???variability???????????(Okamura et al. Int
J Gynecol Obstet 1997.)
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p lt 0.05
7890 Frequency Edge
75 Frequency Edge
50 Frequency Edge
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81??????????????????????
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82PVL?????
83PVL?endotoxin????
84PVL?endotoxin????
85PVL?endotoxin????
86(No Transcript)
87PVL?????
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88PVL?????
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89?????????
90????hANPBNP?PVL
PVL???????????????????????????? ????????????????
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flop????????????Flip flop?????????????????????????
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91Study???
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92??
93?????EPO?PVL
PVL??????????????????????????????? ?????????????
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??????????????????????EPO??????
94EPO (mU/ml)
???
PVL
95PVL???????????
PVL??????????????????????????????????ACE?????? P
VL??????????????????????????????????????????? ???
PVL???????????????????????????????????????????????
?MDA-LDL8-isoprostane????????????????
96(ng/ml)
(IU/l)
ACE
P-?????
(U/l)
(pg/ml)
8-isoprostane
MDA-LDL
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100Textbook Is
Not To Read
But To Revise