DNA STRUCTURE

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DNA STRUCTURE

• HOW WATSON AND CRICK
• FIGURED IT OUT -
• THEY HAD SOME HELP

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CHARGAFFS RATIOS

• CHARGAFF DISCOVERED THE FOLLOWING AFTER ANALZYING
  DNA FROM DIFFFERENT SPECIES
• A T
• C G

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WILKINS FRANKLIN

• FROM WILKINS FRANKLINS X-RAY CRYSTALLOGRAPHY
  IMAGE OF DNA, WATSON CRICK REALIZED THERE WAS
  ROOM
• BETWEEN THE SIDES OF THE LADDER FOR ONLY THREE
  RINGS
• ONE PURINE AND ONE PYRIMIDINE
• BUT HOW DO THEY BIND TOGETHER?

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TWO RINGS PURINES
ONE RING PYRIMIDINES
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They reasoned that the spaces between The sides
of the ladder consisted of Adenine bonding
with Thymine Cytosine bonding with Guanine
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Also that the strands run in an Anti-parallel
fashion
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